Signaling networks and cell cycle control the molecular basis of cancer and other diseases

Signaling networks and cell cycle control the molecular basis of cancer and other diseases / edited by J. Silvio Gutkind.

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Bibliographic Details
Other Authors: Gutkind, J. Silvio
Format: eBook
Language:English
Published: Totowa, N.J. : Humana Press, 2000.
Series:Cancer drug discovery and development.
Ebsco e-book purchased.
Subjects:
Cellular signal transduction.
Cell cycle.
Cellular control mechanisms.
Pathology, Molecular.
Electronic resources (E-books)
Electronic books.
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
This was purchased from Ebsco with a single user license.
Table of Contents:
  • 1 Integrin Signaling / Kenneth M. Yamada, Erik H.J. Danen 1
  • 2 Signal Transduction Through Tyrosine Kinase Growth Factor Receptors / Paolo Fedi, Stuart A. Aaronson 27
  • 3 Signaling from TGF-[beta] Receptors / Anita B. Roberts, Mark P. de Caestecker, Robert J. Lechleider 39
  • 4 The Wnt Signal Transduction Pathway / Grant D. Barish, Bart O. Williams 53
  • 5 Signaling from G-Protein-Coupled Receptors to the Nucleus / Shigetomo Fukuhara, Maria Julia Marinissen, Mario Chiariello, J. Silvio Gutkind 83
  • 6 Proximal Events in T-Cell Activation / Joanne Sloan-Lancaster, Lawrence E. Samelson 99
  • 7 Signal Transduction from the High Affinity IgE Receptor / Reuben P. Siraganian 113
  • 8 Signaling Through Fas (CD95, APO-1) and Related Death Receptors / Richard M. Siegel, David A. Martin, Felicita Hornung, Erastus C. Dudley, Lixin Zheng, Michael J. Lenardo 135
  • 9 Signal Transduction to the Nucleus by MAP Kinase / Roger J. Davis 153
  • 10 The Regulation of MAP Kinase Pathways by MAP Kinase Phosphatases / Kathleen Kelly, Yanfang Chu 165
  • 11 Control of MAPK Signaling by Ste20- and Ste11-Like Kinases / Gary R. Fanger, Thomas K. Schlesinger, Gary L. Johnson 183
  • 12 Ras Signaling and Transformation / Geoffrey J. Clark, John P. O'Bryan, Channing J. Der 213
  • 13 Signaling Pathways Controlled by Rho Family GTP-Binding Proteins / Marc Symons 231
  • 14 PI3-Kinases: Role in Signal Transduction / David A. Fruman, Lewis C. Cantley 247
  • 15 PI3K-Related Kinases: Roles in Cell-Cycle Regulation and DNA Damage Responses / Randal S. Tibbetts, Robert T. Abraham 267
  • 16 Integrative Signaling Through c-Abl: A Tyrosine Kinase with Nuclear and Cytoplasmic Functions / Jean Y.J. Wang 303
  • 17 Src: A Model for Regulation of Intracellular Signaling Molecules / Pamela L. Schwartzberg 325
  • 18 Inhibitors of Protein Kinase C and Related Receptors for the Lipophilic Second Messenger sn-1,2-Diacylglycerol / Peter M. Blumberg, Peter Acs, Dipak K. Bhattacharyya, Patricia S. Lorenzo 347
  • 19 Reactive Oxygen Species in Proliferative Signaling / Toren Finkel, Daniel M. Sullivan 365
  • 20 Sphingolipid Metabolites in Signal Transduction / Sarah Spiegel, Sheldon Milstien 379
  • 21 The Jak/Stat Signaling Cascade: Its Role in the Biological Effects of Interferons / Andrew C. Larner, Andrew Keightley 393
  • 22 Regulation of Cell Growth and Death by p53 / Kevin M. Ryan, Karen H. Vousden 411
  • 23 Regulation of NF-[kappa]B Function: Novel Molecular Targets for Pharmacological Intervention / Frank Mercurio, Anthony M. Manning 429
  • 24 Using Protein-Interaction Domains to Manipulate Signaling Pathways / Bruce J. Mayer 439
  • 25 Protein Tyrosine Kinase Inhibitors as Novel Therapeutic Agents / Alexander Levitzki 453
  • 26 A Pharmacological Approach to the MAP Kinase Cascade / David T. Dudley, Alan R. Saltiel 467
  • 27 Specific Inhibitors of p38 MAP Kinase / Peter R. Young 483
  • 28 Farnesyltransferase Inhibitors: Anti-Ras or Anticancer Drugs? / Adrienne D. Cox, Channing J. Der 501
  • 29 Targeted p53 Gene Therapy-Mediated Radiosensitization and Chemosensitization / Esther H. Chang, Liang Xu, Kathleen F. Pirollo 519
  • 30 Treatment of p53-Deficient Cancers by Adenovirus E1B-Region Mutants: From Basic Research to the Clinic / David H. Kirn 537
  • 31 The Cell Cycle Inhibitor p27 as a Prognostic Marker in Human Tumors and a Novel Target for Therapeutic Intervention / Michele Pagano, Katya Ravid 545
  • 32 Chemical Cyclin-Dependent Kinase Inhibitors: Therapeutic Implications / Edward A. Sausville, Adrian M. Senderowicz 557.

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