Nuclear Factor кB Regulation and Role in Disease

Nuclear Factor кB Regulation and Role in Disease / edited by R. Beyaert.

Seventeen years after its initial description, nuclear factor-KB (NF-KB) endures as one of the most studied transcription factors. NF-KB has attracted widespread interest based on the variety of stimuli that activate it, the diverse genes and bio­ logical responses that it controls, the striking evo...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Beyaert, R. (Editor)
Format: eBook
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2003.
Edition:1st ed. 2003.
Series:Springer eBook Collection.
Subjects:
Immunology.
Animal anatomy.
Biochemistry.
Pharmacy.
Cancer research.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Activators and Target Genes of Rel/NF-?B Transcription Factors — From Bench to Bedside
  • NF-?B Activation by Tumor Necrosis Factor and Interleukin-1
  • NF-?B Activation by CARD Proteins
  • Viruses as Intruders in the Rel/NF-?B Signaling Pathway
  • The I?B Kinase (IKK) Complex
  • The Role of Ubiquitin in NF-?B Signaling
  • New Insights into the Regulation of NF-?B — Roles for Phosphorylation and Acetylation of NF-?B Subunits
  • The Structural Biology of NF-?B
  • Tools to Interfere with NF-?B Activation
  • Regulation of NF-?B by Glucocorticoids
  • Genetic Analysis of NF-?B-dependent Signaling Pathways in Mammalian Cells
  • Delineation of NF-?B Signaling by Gene Targeting
  • The Role of NF-?B in Inflammatory Diseases
  • NF-?B in Genetic Disorders
  • NF-?B in the Vascular System
  • NF-?B in T-lymphocyte Biology
  • NF-?B in the Nervous System
  • NF-?B in Oncogenesis and as a Target for Cancer Therapy
  • Control of Immunity by Rel Proteins in Drosophila.

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