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|a 9781461312352
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|a 10.1007/978-1-4613-1235-2
|2 doi
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|a (DE-He213)978-1-4613-1235-2
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|a Pathophysiology of Heart Failure
|h [electronic resource] /
|c edited by Naranjan S. Dhalla, Pawan K. Singal, Nobuakira Takeda, Robert E. Beamish.
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| 250 |
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|a 1st ed. 1996.
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| 264 |
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1 |
|a New York, NY :
|b Springer US :
|b Imprint: Springer,
|c 1996.
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| 300 |
|
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|a XLII, 578 p.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
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|a online resource
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| 347 |
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|a text file
|b PDF
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|
| 490 |
1 |
|
|a Developments in Cardiovascular Medicine,
|x 0166-9842 ;
|v 168
|
| 490 |
1 |
|
|a Springer eBook Collection
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| 505 |
0 |
|
|a I. Cardiomyopathy and Contractile Dysfunction -- 1. Experimental models of heart failure and cardiomyopathy -- 2. Role of tissue and circulating substance P in cardiovascular injury associated with Mg-deficiency -- 3. Functional and metabolic effects of norepinephrine on the rat heart -- 4. Interventions in experimentally induced diabetic cardiomyopathy -- 5. Diabetes as a risk factor for cardiovascular disease: Experimental models -- 6. Ethanol-induced hypertension: the role of Acetaldehyde -- 7. Abnormalities in cardiac contractile proteins and cardiac dysfunction -- 8. Role of the slow sodium channel in hereditary cardiomyopathy -- 9. Cardiac contractile failure caused by disturbances in myofibrillar energy supply and pathogenesis of cardiomyopathies -- 10. Changes in contractile proteins under oxidative stress -- 11. Antioxidants and the heart -- 12. Gene expression of cardiac myocytes: a pharmacologic target for the failing heart? -- II. Calcium-Related Events and Heart Dysfunction -- 13. Regulation of slow Ca2+ channels of myocardial cells by cyclic nucleotides and phosphorylation -- 14. Multiple roles for the membrane-associated Ca2+/calmodulin-dependent protein kinase in the regulation of sarcoplasmic reticulum function in heart muscle -- 15. Calreticulin, a multifunctional Ca2+ binding protein of smooth muscle sarcoplasmic reticulum membranes -- 16. Intracellular Ca2+ transients in response to step length changes in aequorin-injected ferret papillary muscles -- 17. Initial changes in ?-adrenergic receptor function during development of rapid ventricular pacing-induced heart failure -- 18. Impaired cellular signaling of the adenylyl cyclase and the phosphoinositide pathway in septic cardiomyopathy -- 19. Defective G-protein expression and adenylyl cyclase in genetic and experimental hypertension -- 20. Electrophysiological studies of wild-type and mutant Na+-Ca2+ exchange proteins -- 21. Cardiac sarcolemmal Na+/H+ exchange after a myocardial infarction in the rat -- 22. Myocardial Na, K-ATPase concentration and heart failure -- 23. The cytosolic calcium-force relation of vascular smooth muscle during the contraction and the relaxation -- III. Ischemia and Cellular Interactions -- 24. Ventricular remodeling following coronary artery constriction and hypertension -- 25. Collagenous proteins in scar tissue subsequent to myocardial infarction -- 26. Structural remodeling and functional changes in chronic hypoxia-induced right ventricular hypertrophy -- 27. Mechanism of openings and role of the ATP-sensitive K+ channels during myocardial ischemia/reperfusion -- 28. The contribution of K+ currents to electrical heterogeneity across the canine ventricular wall under normal and ischemic conditions -- 29. Diabetic state reduces ischemic K+ loss and H+ efflux in isolated rat hearts -- 30. Divergent effects of receptor- and nonreceptor-mediated activators of sodium-hydrogen exchange on reperfusion-induced contractile dysfunction -- 31. Heart cells in culture for studying anoxia and “simulated ischemia” at the cellular level -- 32. Cardioprotection and basic fibroblast growth factor -- 33. The heart and nitric oxide -- 34. The endothelium and the regulation of coronary blood flow -- 35. Signal transduction in vascular smooth muscle: synergistic interactions between receptors and transduction pathways -- 36. Modulation of peak aerobic capacity by the peripheral circulation during the course of the syndrome of congestive heart failure.
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| 520 |
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|a Pathophysiology of Heart Failure brings together leading basic scientists and clinicians, presenting new approaches to this complex problem, involving cardiomyopathic processes and ischemia perfusion injury. The result is a synthesis of state-of-the-art information on molecular biology, cellular physiology and structure-function relationships in the cardiovascular system. The role which excess intracellular calcium plays in the genesis of cardiac dysfunction is described as a fundamental mechanism underlying heart failure; one which may lead to improved prevention and treatment. Audience: Clinical and experimental cardiologists will find the book a helpful source of ideas and inspiration.
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| 590 |
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|a Loaded electronically.
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| 590 |
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|a Electronic access restricted to members of the Holy Cross Community.
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| 650 |
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0 |
|a Cardiology.
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| 690 |
|
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|a Electronic resources (E-books)
|
| 700 |
1 |
|
|a Dhalla, Naranjan S.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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| 700 |
1 |
|
|a Singal, Pawan K.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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| 700 |
1 |
|
|a Takeda, Nobuakira.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
|
| 700 |
1 |
|
|a Beamish, Robert E.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
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|t Springer eBooks
|
| 830 |
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|a Developments in Cardiovascular Medicine,
|x 0166-9842 ;
|v 168
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| 830 |
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|a Springer eBook Collection.
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