Analysis of Microarray Gene Expression Data by Mei-Ling Ting Lee.

After genomic sequencing, microarray technology has emerged as a widely used platform for genomic studies in the life sciences. Microarray technology provides a systematic way to survey DNA and RNA variation. With the abundance of data produced from microarray studies, however, the ultimate impact o...

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Bibliographic Details
Main Author: Mei-Ling Ting Lee (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 2004.
Edition:1st ed. 2004.
Series:Springer eBook Collection.
Subjects:
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.

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505 0 |a DNA, RNA, Protein, and Gene Expression -- Microarray Technology -- Inherent Variability in Microarray Data -- Background Noise -- Transformation and Normalization -- Missing Values in Microarray Data -- Saturated Intensity Readings in Microarray Data -- Experimental Design -- Anova Models for Michrorray Data -- Multiple Testing in Microarray Studies -- Permutation Tests in Microarray Data -- Bayesian Methods for Microarray Data -- Power and Sample Size Considerations at the Planning Stage -- Cluster Analysis -- Principal Components and Singular Value Decomposition -- Self-organizing Maps -- Discrimination and Classification -- Artificial Neural Networks -- Support Vector Machines. 
520 |a After genomic sequencing, microarray technology has emerged as a widely used platform for genomic studies in the life sciences. Microarray technology provides a systematic way to survey DNA and RNA variation. With the abundance of data produced from microarray studies, however, the ultimate impact of the studies on biology will depend heavily on data mining and statistical analysis. The contribution of this book is to provide readers with an integrated presentation of various topics on analyzing microarray data. 
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