Molecular Basis and Thermodynamics of Bioelectrogenesis

Molecular Basis and Thermodynamics of Bioelectrogenesis by E. Schoffeniels, D. G. Margineanu.

Despite the fact that many years have elapsed since the first microcalorimetric measurements of an action potential were made, there is still among the research workers involved in the study of bioelectrogenesis a complete overlooking of the most fundamental principle governing any biological phenom...

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Bibliographic Details
Main Authors: Schoffeniels, E. (Author), Margineanu, D. G. (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 1990.
Edition:1st ed. 1990.
Series:Topics in Molecular Organization and Engineering, 5
Springer eBook Collection.
Subjects:
Physical chemistry.
Biochemistry.
Neurosciences.
Biophysics.
Biological physics.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • I The Description in Physico-Chemical Terms of Nervous System Properties
  • I.1. Living systems as dissipative structures with local quasi equilibrium
  • I.2. Information flows in living systems
  • I.3. Evolution of the ideas about bioelectrogenesis. A brief account
  • References
  • II Cell Membranes and Bioelectrogenesis
  • II.1. The ubiquitous cellular component
  • II.2. Membrane molecular components and their dynamics
  • II.3. Silent and excitable membranes
  • References
  • III Phenomenological Aspects of Bioelectricity
  • III.1. Resting potential of the cells
  • III.2. The passive propagation of potential changes. Axons as electric cables
  • III.3. Regenerative propagation of action potentials in excitable membranes
  • III.4. Intercellular transmission of excitation
  • III.5. An overview of bioelectric phenomena
  • References
  • IV Molecular Approaches of Bioelectricity
  • A. Intermediary metabolism in brain
  • B. Control of glycolysis
  • C. Non oxidative consumption of glucose during neural activity
  • D. The pentose shunt
  • E. The amino acids pool
  • F. Concluding remarks
  • References
  • V Puzzle of Nerve Impulse Thermodynamics
  • V.1. Oxygen consumption and heat production inactive nerve
  • V.2. Energy dissipation by Na+/K+ pumps in nerves
  • V.3. Energy changes during the action potential
  • V.4. Thermodynamic inconsistency of the kinetics of n, m and h parameters
  • References
  • VI Thiamine Triphosphate as the Specific Operative Substance in Spike-Generation
  • Conclusion
  • References
  • VII. Merging Electrophysiology and Molecular Approaches
  • VII.1. Single-channel recording
  • VII.2. The structure of channel proteins
  • VII.3. From molecular mechanisms to complex brain functions
  • VII.4. Levels of unitary events
  • References
  • Index of Names
  • Index of Subjects.

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