Potassium Channels in Cardiovascular Biology

Potassium Channels in Cardiovascular Biology edited by Stephen L. Archer, Nancy J. Rusch.

Potassium channels (K+) are membrane-spanning proteins which serve many important functions and are becoming a hot topic in physiology. K+ channels determine or modulate many functions of vascular smooth muscle, endothelial and inflammatory cells, and thus are central to regulation of arterial tone...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Archer, Stephen L. (Editor), Rusch, Nancy J. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 2001.
Edition:1st ed. 2001.
Series:Springer eBook Collection.
Subjects:
Cardiology.
Pharmacology.
Human physiology.
Medical biochemistry.
Biochemistry.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • 1 Evolution of Potassium Channel Proteins
  • 2 Three-Dimensional Structure of the K+ Channel Pore: Basis for Ion Selectivity and Permeability
  • 3 Molecular Biology of Voltage-Gated K+ Channels
  • 4 Molecular Biology of High-Conductance, Ca2+-Activated Potassium Channels
  • 5 Molecular Biology of Inward Rectifier and ATP-Sensitive Potassium Channels
  • 6 Design and Use of Antibodies for Mapping K+ Channel Expression in the Cardiovascular System
  • 7 Molecular Methods for Evaluation of K+ Channel Expression and Distribution in the Heart
  • 8 Concepts for Patch-Clamp Recording of Whole-Cell and Single-Channel K+ Currents in Cardiac and Vascular Myocytes
  • 9 The Patch-Clamp Technique for Measurement of K+ Channels in Xenopus Oocytes and Mammalian Expression Systems
  • 10 Heteromultimer Formation in Native K+ Channels
  • 11 Use of Transgenic and Gene-Targeted Mice to Study K+ Channel Function in the Cardiovascular System
  • 12 Pharmacology of Voltage-Gated K+ Channels
  • 13 Pharmacology of High-Conductance, Ca2+ -Activated Potassium Channels
  • 14 Pharmacology of Small-Conductance, Calcium-Activated K+ Channels
  • 15 Molecular Pharmacology of ATP-Sensitive K+ Channels: How and Why?
  • 16 Overview: Molecular Physiology of Cardiac Potassium Channels
  • 17 Molecular Mechanisms Controlling Functional Voltage-Gated K+ Channel Diversity and Expression in the Mammalian Heart
  • 18 Voltage-Gated Potassium Channels in the Myocardium
  • 19 Inward Rectifying and ATP-Sensitive K+ Channels in the Ventricular Myocardium
  • 20 Cholinergic and Adrenergic Modulation of Cardiac K+ Channels
  • 21 Cardiac K+ Channel Expression and Function at Birth and in the Neonate
  • 22 Overview: Physiological Role of K+ Channels in the Regulation of Vascular Tone
  • 23 Modulation of Vascular K+ Channels by Extracellular Messengers
  • 24 Delayed Rectifier K+ Channels of Vascular Smooth Muscle: Characterization, Function, and Regulation by Phosphorylation
  • 25 Potassium Channels in the Circulation of Skeletal Muscle
  • 26 Regulation of Cerebral Artery Diameter by Potassium Channels
  • 27 The Role of Potassium Channels in the Control of the Pulmonary Circulation
  • 28 Potassium Channels in the Renal Circulation
  • 29 Potassium Channels in the Coronary Circulation
  • 30 Vascular K+ Channel Expression and Function at Birth and in the Neonate
  • 31 Overview: Potassium Channels in Vascular Endothelial Cells
  • 32 Single-Channel Properties of Ca2+-Activated K+ Channels in the Vascular Endothelium
  • 33 Endothelial Cell K+ Channels, Membrane Potential, and the Release of Vasoactive Factors from the Vascular Endothelium
  • 34 Activation of Vascular Smooth Muscle K+ Channels by Endothelium-Derived Factors
  • 35 Overview: Role of Potassium Channels in Cardiac Arrthythmias
  • 36 The Molecular Basis of the Long QT Syndrome
  • 37 Altered K+ Channel Expression in the Hypertrophied and Failing Heart
  • 38 Role of ATP-Sensitive K+ Channels in Cardiac Preconditioning
  • 39 Therapeutic Potential of ATP-Sensitive K+ Channel Openers in Cardiac Ischemia
  • 40 Altered Expression and Function of Kv Channels in Primary Pulmonary Hypertension
  • 41 Anorectic Drugs and the Vasculature
  • 42 Induction of Ca2+-Activated K+ Channel Expression during Systemic Hypertension: Protection against Pathological Vasoconstriction
  • 43 Antisense Approaches and the Modulation of Potassium Channel Function in the Cardiovascular System.

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