Aging and Recovery of Function in the Central Nervous System

Aging and Recovery of Function in the Central Nervous System by Stephen W. Scheff.

The mammalian central nervous system is a remarkable structure which has attracted many new investigators, as evidenced by the dramatic increase in scientific publications dealing with neurobiology. Every day basic scientists conduct new and exciting experiments, resulting in remarkable discoveries...

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Bibliographic Details
Main Author: Scheff, Stephen W. (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 1984.
Edition:1st ed. 1984.
Series:Springer eBook Collection.
Subjects:
Geriatrics.
Life sciences.
Neurobiology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • 1 Longevity, Disease, and Autoimmune Reactions following Focal Cortical Injuries
  • 1. Introduction
  • 2. Longevity
  • 3. Disease Profiles
  • 4. Neuron-Binding Antibodies
  • 5. Conclusions
  • References
  • 2 Aging and Hypothalamic Regulation of Metabolic, Autonomic, and Endocrine Function
  • 1. Introduction
  • 2. Structure and Function of the Hypothalamus
  • 3. Hypothalamic Theories of Aging
  • 4. Effects of Hypothalamic Damage
  • 5. Aging-Hypothalamic Damage Comparisons
  • 6. Overview and Summary
  • References
  • 3 Morphological Measurements in the Aging Rat Cerebral Cortex
  • 1. Introduction
  • 2. Neuronal and Glial Cell Number Changes during Aging
  • 3. Aging and Impoverishment
  • 4. Summary
  • References
  • 4 Morphologic Aspects of Brain Damage in Aging
  • 1. Introduction
  • 2. Reactive Synaptogenesis in Young Adult Animals
  • 3. Normal Anatomy of the Aged Hippocampus
  • 4. Reactive Synaptogenesis in the Dentate Gyrus of Aged Animals
  • 5. Adrenergic Sprouting in the Limbic System of Aged Rats
  • 6. Possible Mechanisms for Reduced Sprouting Capacity
  • 7. Conclusion
  • References
  • 5 Relationship of the Raphe and Suprachiasmatic Nuclei to Serotonin Facilitation of Cyclic Reproductive Functions in Aging Female Rats
  • 1. Introduction
  • 2. Temporal Patterns of Hypothalamic 5-HT and Cyclic Reproductive Function
  • References
  • 6 Behavioral Consequences of Neuronal Plasticity following Injury to Nigrostriatal Dopaminergic Neurons
  • 1. Introduction
  • 2. Approaches to Studying the Neural Events Mediating Behavioral Recovery
  • 3. Inattention to Stimuli
  • 4. Neglect after Nigrostriatal Injury as a Model System
  • 5. Neural Events Contributing to Recovery of Sensorimotor Functions
  • 6. Future Directions
  • 7. Conclusions
  • References
  • 7 Do Rats Have Hypotheses? A Developmental and Means-Ends Analyses Approach to Brain Damage, Recovery of Function, and Aging
  • 1. Introduction
  • 2. Methods
  • 3. Results
  • 4. Discussion
  • References
  • 8 Age, Brain Damage, and Behavioral Recovery
  • 1. Introduction
  • 2. Spatial Alternation Learning
  • 3. Emotional Reactivity
  • 4. DRL-20 Performance
  • 5. Discussion
  • References
  • 9 Age and Recovery from Brain Damage: A Review of Clinical Studies
  • 1. Functional Plasticity after Early Brain Injury
  • 2. Head Injury through the Lifespan
  • 3. Pathophysiology of Closed-Head Injury in Relation to Age
  • 4. Effects of Age on Outcome after Head Injury
  • 5. Early and Late Neurobehavioral Effects of Head Injury
  • 6. Directions for Future Research
  • References
  • 10 Recovery of Function in Senile Dementia of the Alzheimer Type
  • 1. Introduction
  • 2. Alzheimer’s Disease: The Clinical and Biochemical Problem
  • 3. Behavioral Strategies for Cognitive Deficits of Alzheimer’s Disease
  • 4. Pharmacologic Intervention in Alzheimer’s Disease
  • 5. Cholinergic Systems, Trophic Substances, and Potential Therapies for Alzheimer’s Disease
  • 6. Pharmacologic Enhancement of a Trophic Factor Effect
  • References.

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