Anticancer Drug Resistance Advances in Molecular and Clinical Research

Anticancer Drug Resistance Advances in Molecular and Clinical Research / edited by Lori J. Goldstein, Robert F. Ozols.

Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, testicular cancer and Hodgkin's disease. We are still, however, confronted with over 500,000 cancer-related deaths per year. Clearly, the phenomeno...

Full description

Saved in:
Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Goldstein, Lori J. (Editor), Ozols, Robert F. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 1994.
Edition:1st ed. 1994.
Series:Cancer Treatment and Research, 73
Springer eBook Collection.
Subjects:
Oncology  .
Cancer research.
Pharmacology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • 1. Genetics of Drug Resistance
  • 2. P-Glycoprotein Homologues
  • 3. Role of Protein Kinase C in Multidrug Resistance
  • 4. Transcriptional Regulation of Multidrug Resistance Gene Expression
  • 5. In vitro Models of Multidrug Resistance
  • 6. In vivo Models of P-Glycoprotein-Mediated Multidrug Resistance
  • 7. Molecular Diagnosis of Multidrug Resistance
  • 8. Clinical Reversal of Multidrug Resistance
  • 9. Role of Gene Amplification in Drug Resistance
  • 10. Biochemical Modulation as an Approach to Reversal of Antimetabolite Resistance
  • 11. Mechanisms of Acquired Resistance to Cisplatin
  • 12. Mechanisms of Resistance to Alkylating Agents
  • 13. Mechanisms of Resistance to Topoisomerase Inhibitors.

Similar Items