Myasthenia Gravis Disease Mechanism and Immunointervention

Myasthenia Gravis Disease Mechanism and Immunointervention / edited by Premkumar Christadoss.

Autoimmune myasthenia gravis (MG) is a classical autoimmune disease, for which the target antigen, nicotinic acetylcholine receptor, has been cloned, sequenced and biochemically characterized. Antibodies to acetylcholine receptors destroy acetylcholine receptor at the neuromuscular junction, thus le...

Full description

Saved in:
Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Christadoss, Premkumar (Editor)
Format: eBook
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2000.
Edition:1st ed. 2000.
Series:Springer eBook Collection.
Subjects:
Internal medicine.
Immunology.
Neurology .
Biochemistry.
Pathology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • I. Mechanisms of Disease
  • 1. Current Concepts on the Structure of Acetylcholine Receptor with Relevance to Myasthenia Gravis and Experimental Autoimmune Myasthenia Gravis Pathogenesis
  • 2. Tolerance of a Transgenic Self Antigen Expressed in the Thymus: Implication for Myasthenia gravis
  • 3. Low Levels of Acetylcholine Receptor Delta-subunit message and Protein in Human Thymus Suggests the Occurrence of “Triplet Receptors” in Thymic Myoid Cells
  • 4. Aberrant Encounter of Acetylcholine Receptor-Expressing Cells with the Lymphoid Infiltrates in the Thymus of Myasthenia Gravis Patients
  • 5. Expression of the Acetylcholine Receptor ?-Subunit Gene is Associated with Paraneoplastic Myasthenia Gravis in Mixed Thymoma
  • 6. Abnormal Thymocyte Development and Neurofilament-Reactive Thymocytes in Thymoma
  • 7. Cellular Mechanisms of Target Antigen Attack in Experimental Autoimmune Myasthenia Gravis
  • Anti-Acetylcholine Receptor CD4+ T Cells in Myasthenia Gravis: Epitope repertoire and T cell receptor gene usage
  • 9. Molecular Mechanisms of MHC Associations with Myasthenia Gravis
  • 10. Non-MHC Genetic Polymorphisms in Human Autoimmune Myasthenia Gravis
  • 11. Experimental Myasthenia Gravis in Mice: The Role of Costimulatory Molecules
  • 12. Passive Myasthenia Gravis Induced in SCID Mice by Transfer of Blood Cells From Myasthenic Patients
  • 13. Evidence for an Upregulation of Acetylcholine Receptor Messenger Subunits Triggered by Antibody-Mediated Receptor Internalization in Human Myasthenia Gravis Muscles
  • II. Immunointervention
  • 14. Oral Administration of Peptide T?l46-162 Prevents EAMG in Mice
  • 15. Protective Role of Th2 Cells in Mouse Experimental Myasthenia Gravis
  • 16. Antigen-Specific Therapy of Experimental Autoimmune Myasthenia Gravis: Mucosal tolerance with recombinant fragments of the human acetylcholine receptor
  • 17. Immunomodulation of Myasthenia Gravis Associated Autoimmune Responses by an Altered Peptide Ligand: Mechanisms of action
  • 18. Antigen-Specific Immunointervention in Experimental Myasthenia Gravis.

Similar Items