Antimalarial Drugs I Biological Background, Experimental Methods, and Drug Resistance.

Antimalarial Drugs I Biological Background, Experimental Methods, and Drug Resistance.

Of all the parasitic diseases that beset man in the warmer parts of the world, malaria is still the major cause of morbidity and mortality. In spite of intensive efforts to interrrupt its transmission malaria still threatens over 800 million people, more than one-fifth of the world's population...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1984.
Edition:1st ed. 1984.
Series:Handbook of Experimental Pharmacology, 68 / 1
Springer eBook Collection.
Subjects:
Pharmacology.
Medical microbiology.
Pharmacy.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • The Malaria Parasites
  • 1 Life Cycles
  • 2 Metabolism
  • 3 In Vitro Culture Techniques
  • Host Responses to Malaria
  • 4 Immunity
  • 5 Clinical Pathology
  • Experimental Models
  • 6 In Vitro Techniques for Antimalarial Development and Evaluation
  • 7 Use of Avian Malarias (In Vivo)
  • Chapte 8 Rodent Malaria Models
  • 9 Malaria Models in Simian Hosts
  • 10 Surrogate Models for Antimalarials
  • 11 Interactions Between Chemotherapy and Immunity
  • Preclinical and Clinical Trial Techniques
  • 12 Preclinical Testing
  • 13 Clinical Trials — Phases I and
  • 14 Clinical Trials — Phases III and IV and Field Trials
  • 15 Pharmacogenetic Factors in Antimalarial Drug Testing
  • Antimalarial Drug Resistance
  • 16 History and Current Status of Drug Resistance
  • 17 Evaluation of Drug Resistance in Man
  • 18 Experimental Production of Drug Resistance.

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