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|a Ben-Naim, Arieh Y.
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|a Cooperativity and Regulation in Biochemical Processes
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|c by Arieh Y. Ben-Naim.
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|a 1st ed. 2001.
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|a 1 Introducing the Fundamental Concepts -- 2 The Binding Isotherm -- 3 Adsorption on a Single-Site Polymer with Conformational Changes Induced by the Binding Process -- 4 Two-Site Systems: Direct and Indirect Cooperativity -- 5 Three-Site Systems: Nonadditivity and Long-Range Correlations -- 6 Four-Site Systems: Hemoglobin -- 7 Large Linear Systems of Binding Sites -- 8 Regulatory Enzymes -- 9 Solvent Effects on Cooperativity -- Appendices -- A. Pair and Triplet Correlations between Events -- B. Localization of the Adsorbent Molecules and Its Effect on the Binding Isotherm -- C. Transition from Microstates to Macrostates -- D. First-Order Correction to Nonideality of the Ligand’s Reservoir -- E. Relative Slopes of Equilibrated and “Frozen-in” BIs in a Multimacrostate System -- F. Spurious Cooperativity in Single-Site Systems -- G. The Relation between the Binding Isotherm and the Titration Curve for Two-Site Systems -- H. Fitting Synthetic Data -- I. A Comment on the Nomenclature -- J. Average Binding Constants and Correlation Functions -- K. Utility Function in a Binding System -- Abbreviations Used in the Text -- References.
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|a Bioorganic chemistry.
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|a Biochemistry.
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