N-Oxidation of Drugs Biochemistry, pharmacology, toxicology

N-Oxidation of Drugs Biochemistry, pharmacology, toxicology / by P. Hlavica, L.A. Damani.

Saved in:
Bibliographic Details
Main Authors: Hlavica, P. (Author), Damani, L.A (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 1991.
Edition:1st ed. 1991.
Series:Springer eBook Collection.
Subjects:
Pharmacology.
Biochemistry.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • One Analysis of N-Oxidized Products
  • 1 Formation of aromatic amine free radicals by prostaglandin hydroperoxidase and peroxyl radicals: analysis by ESR and stable end products
  • 2 The application of 15N-NMR in the analysis of N-oxygenated amidines and guanidines
  • 3 Radioimmunoassay and other methods for trace analysis of N-oxide compounds
  • Two Enzymology of N-Oxidation
  • 4 Mechanism, multiple forms and substrate specificities of flavincontaining mono-oxygenases
  • 5 On the genetic polymorphism of the flavin-containing monooxygenase
  • 6 Factors regulating the activity of the rabbit lung flavincontaining mono-oxygenase
  • 7 Human pharmacogenetics of nitrogen oxidations
  • 8 Microbial N-hydroxylases
  • 9 Roles of aminium radical intermediates in the biotransformation of dihydropyridines, cycloalkylamines, and N,N-dimethylanilines by cytochrome P-450 enzymes
  • 10 The role of cytochrome P-450 in the biological nuclear N-oxidation of aminoazaheterocyclic drugs and related compounds
  • 11 New aspects of the microsomal N-hydroxylation of benzamidines
  • 12 Studies on the N-oxidation of phentermine: evidence for an indirect pathway of N-oxidation mediated by cytochrome P-450
  • 13 Molecular activation mechanisms involved in arylamine cytotoxicity: peroxidase products
  • Three Reductions and Conjugations of N-Oxygenated Compounds
  • 14 Reduction and conjugation reactions of N-oxides
  • 15 In vivo metabolism of N-oxides
  • 16 Purification and characterization of rat hepatic acetyltransferase
  • Four Bioactivation of Nitrogenous Compounds and Cell Toxicity
  • 17 Metabolism and activation of nitrosamines catalysed by cytochrome P-450 isoenzymes
  • 18 Cytochrome P-450-catalysed activation of carcinogenic aromatic amines and amides
  • 19 Comparative biochemistry of cytochrome P-450 species responsible for the activation of mutagenic food-derived heterocyclic amines
  • 20 Specificity and inducibility of cytochrome P-450 catalysing the activation of food-derived mutagenic heterocyclic amines
  • 21 Monoamine oxidase-mediated activation of MPTP and related compounds
  • 22 Activation of aromatic amines by oxyhaemoglobin
  • 23 Relevance of primary and secondary nitroxide radicals in biological oxidations
  • 24 Molecular approaches to evaluation of the risk of aromatic amineinduced bladder cancer: smoking related carcinogen-DNA adducts in biopsied samples of human urinary bladder
  • 25 The role of N-oxidation by leukocytes in drug-induced agranulocytosis and other drug hypersensitivity reactions
  • 26 Phototoxic effects of N-oxidized drugs and related compounds.

Similar Items