Bone Metastasis and Molecular Mechanisms Pathophysiology

Bone Metastasis and Molecular Mechanisms Pathophysiology / edited by Gurmit Singh, William Orr.

Patients with advanced breast or prostate cancers usually develop bone metastases. The principal complications resulting from metastatic bone disease are pain, spinal cord compression, pathologic fractures and bone marrow suppression. Improving the management of bone metastases is crucial to quality...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Singh, Gurmit (Editor), Orr, William (Editor)
Format: eBook
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2004.
Edition:1st ed. 2004.
Series:Cancer Metastasis - Biology and Treatment, 6
Springer eBook Collection.
Subjects:
Oncology  .
Cancer research.
Pathology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • 1 Models of Breast Cancer Metastasis to Bone: Characterization of a Clinically Relevant Model
  • 2 Quantitation of Bone Metastasis in Experimental Systems
  • 3 Comparative Morphometric Study on Bone Remodeling in Human Specimens and in Experimental Models of Metastatic Bone Disease
  • 4 Clinical Modalities for the Diagnosis, Characterization and Detection of Bone Metastases
  • 5 Metastasis in the Bone Marrow Microenviroment
  • 6 The Role of Tumor-Associated Macrophages in Metastasis-Associated Osteolysis
  • 7 The Malignant Hierarchy in Multiple Myeloma: Relationships between Malignant Cells and Bone Disease
  • 8 Angiogenesis and Lymphangiogenesis in Metastatic Bone Disease: A Matter of Networking
  • 9 Prostate Cancer: Models for Developing Novel Therapeutic Approaches
  • 10 Potential Therapeutic Targets for Bone Metastasis
  • 11 OPG, RANK and RANKL in Bone Metastasis and Cancer-Associated Osteolysis
  • 12 Role of Matrix Metalloproteinases in Bone Metastasis from Human Breast and Prostate Cancer
  • 13 The Role of Bisphosphonates in Bone Metastasis.

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