Vanadium Compounds: Biochemical and Therapeutic Applications edited by Ashok K. Srivastava, Jean-Louis Chiasson.

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Srivastava, Ashok K. (Editor), Chiasson, Jean-Louis (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 1995.
Edition:1st ed. 1995.
Series:Developments in Molecular and Cellular Biochemistry ; 16
Springer eBook Collection.
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Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • I: Chemistry
  • The chemistry of peroxovanadium compounds relevant to insulin mimesis
  • Vanadium chemistry and biochemistry of relevance for use of vanadium compounds as antidiabetic agents
  • Peroxo heteroligand vanadates(V): Synthesis, spectra-structure relationships, and stability toward decomposition
  • Chemically and photochemically initiated DNA cleavage by an insulin-mimetic bisperoxovanadium complex
  • II: Biochemical and physiological studies
  • Insulin-like actions of vanadate are mediated in an insulin-receptor-independent manner via non-receptor protein tyrosine kinases and protein phosphotyrosine phosphatases
  • Peroxovanadium compounds: Biological actions and mechanism of insulin-mimesis
  • Unique and selective mitogenic effects of vanadate on SV40-transformed cells
  • Vanadium salts stimulate mitogen-activated protein (MAP) kinases and ribosomal S6 kinases
  • Protective effect of vanadate on oxyradical-induced changes in isolated perfused heart
  • In vivo effects of vanadate on hepatic glycogen metabolizing and lipogenic enzymes in insulin-dependent and insulin-resistant diabetic animals
  • The relationship between insulin and vanadium metabolism in insulin target tissues
  • Modulation of insulin action by vanadate: Evidence of a role for phosphotyrosine phosphatase activity to alter cellular signaling
  • Reversal of defective G-proteins and adenylyl cyclase/cAMP signal transduction in diabetic rats by vanadyl sulphate therapy
  • Effects of vanadate on the expression of genes involved in fuel homeostasis in animal models of Type I and Type II diabetes
  • Decrease in protein tyrosine phosphatase activities in vanadate-treated obese Zucker (fa/fa) rat liver
  • Evidence for selective effects of vanadium on adipose cell metabolism involving actions on cAMP-dependent protein kinase
  • The enhancement by pervanadate of tyrosine phosphorylation on prostatic proteins occurs through the inhibition of membrane-associated tyrosine phosphatases
  • Contractile effects of vanadate on aorta rings from virgin and pregnant rats
  • In vivo modulation of N-myristoyltransferase activity by orthovanadate
  • Regulation and control of glucose overutilization in erythrocytes by vanadate
  • In vitro and in vivo antineoplastic effects of ortrovanadate
  • Membrane — vanadium interaction: A toxicokinetic evaluation
  • III: Potential use in therapy and toxicological studies
  • Increased potency of vanadium using organic ligands
  • In vivo effects of peroxovanadium compounds in BB rats
  • Long-term antidiabetic activity of vanadyl after treatment withdrawal: Restoration of insulin secretion?
  • Long-term correction of STZ-diabetic rats after short-term i.p. VOSO4 treatment: Persistence of insulin secreting capacities assessed by isolated pancreas studies
  • Antihypertensive effects of vanadium compounds in hyperinsulinemic, hypertensive rats
  • Vanadate induces normolipidemia and a reduction in the levels of hepatic iipogenic enzymes in obese Zucker rat
  • In vivo and in vitro studies of vanadate in human and rodent diabetes mellitus
  • Toxicology of vanadium compounds in diabetic rats: The action of chelating agents on vanadium accumulation
  • Index to Volume 153.