Antimutagenesis and Anticarcinogenesis Mechanisms by Delbert M. Shankel, Philip E. Hartman, Tsuneo Kada, Alexander Hollaender, Claire M. Wilson, Gregory Kuny.

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Bibliographic Details
Main Authors: Shankel, Delbert M. (Author), Hartman, Philip E. (Author), Kada, Tsuneo (Author), Hollaender, Alexander (Author), Wilson, Claire M. (Author), Kuny, Gregory (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 1986.
Edition:1st ed. 1986.
Series:Basic Life Sciences ; 39
Springer eBook Collection.
Subjects:
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.

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505 0 |a Keynote Address -- Carcinogens and Anticarcinogens -- Activation and Inactivation of Mutagens and Carcinogens– –Part I -- The Relation of Activation and Inactivation to Antimutagenic Processes -- Cancer and Free Radicals -- Cytochromes P-450 and the Activation and Inactivation of Mutagens and Carcinogens -- Alteration of Mutagenic Potentials by Peroxidase, Catalase, and Superoxide Dismutase -- Activation and Inactivation of Mutagens and Carcinogens– –Part II -- Effects of Vitamins C and E on Carcinogen Formation and Action, and Relationship to Human Cancer -- Modifiers of Endogenous Nitrosamine Synthesis and Metabolism -- Glutathione Transferases and Carcinogenesis -- Natural Environmental Antimutagens -- Introduction: Natural Environmental Antimutagens -- Antioxidants/Antimutagens in Foods -- Role of Enzymes in Antimutagenes is of Human Saliva and Serum -- Isolation and Identification of Higher Plant Agents Active in Antimutagenic Assay Systems: Glycyrrhiza glabra -- Mechanism of Action of Antimutagens and Anticarcinogens -- Interception of Toxic Agents/Mutagens/Carcinogens: Some of Nature’s Novel Strategies -- Antimutagens and Their Modes of Action -- Avoidance of Errors in Dna -- Introduction: Avoidance of Spontaneously Occurring Errors in DNA -- Introduction: Avoidance of Errors After DNA Damage -- Alkylation and Oxidative Damages to DNA: Constitutive and Inducible Repair Systems -- Molecular Mechanism of Adaptive Response to Alkylating Agents -- Nucleotide Excision Repair Genes from the Yeast Saccharomyces cerevisiae -- The Fixation of Errors -- Introduction: Molecular Basis of Genomic Stability and Change -- Genetic Analyses of the Roles of UmuDC and MucAB in Mutagenesis -- Mechanisms of Spontaneous Mutagenesis: Clues from Altered Mutational Specificity in DNA Repair-Defective Strains -- Genetics and Molecular Biology of Mammalian Cells– –Part I -- Introduction: Comparative Responses to DNA Damage in Bacteria and Mammalian Cells -- Inducible Cellular Responses to DNA Damage in Mammalian Cells -- Single-Base Mutations Associated with Mouse Lymphomas -- The Mouse Mutant “Wasted”: An Animal Model for Ataxia-Telangiectasia -- Genetics and Molecular Biology of Mammalian Cells– –Part II -- Introduction: Oxygen Metabolism, DNA Repair, and the Origin of Spontaneous Genetic Instability -- Multiple Inducible Cytochromes P-450 in Yeast -- DNA Repair Genes of Mammalian Cells -- Genetic and Chemical Factors Affecting Chemical Mutagenesis in Cultured Mammalian Cells -- Mechanisms of Carcinogenicity and Anticarcinogenicity––Part I -- Mechanisms of Carcinogenicity and Anticarcinogenicity: Role of Dietary Components -- Reducing the Genotoxic Damage in the Oral Mucosa of Betel Quid/Tobacco Chewers -- The Concentration of Bile Acids in the Fecal Stream as a Risk Factor for Colon Cancer -- Hormones and Dietary Factors Controlling Gene Activation and Expression in Carcinogenesis -- Dietary Promoters and Antipromoters -- Mechanisms of Carcinogenicity and Anticarcinogenicity– –Part II -- A Mutagen Is a Mutagen, Not Necessarily a Carcinogen -- DNA Repair and Replication in Xeroderma Pigmentosum and Related Disorders -- Role of Intercellular Communication in Modifying the Consequences of Mutations in Somatic Cells -- Mechanisms of Carcinogenicity and Anticarcinogenicity– –Part III -- Genetic Aspects of Cancer Epidemiology -- Protective Effects of Beta-Carotene Against Psoralen Phototoxicity: Relevance to Protection Against Carcinogenesis -- Anticarcinogenic and Other Protective Effects of Dithiolthiones -- Antioxidants as Antitumor Promoters -- Future Directions for Research in Antimutagenesis and Anticarcinogenesis -- Introduction: Future Directions for Research in Antimutagenesis and Anticarcinogenesis -- Inhibitors of Mutagenesis and Their Relevance to Carcinogenesis -- Population Consequences of Mutagenesis and Antimutagenesis -- A Summary––And a Look Ahead -- Poster Abstracts -- Organizing Committee. 
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