Antimutagenesis and Anticarcinogenesis Mechanisms

Antimutagenesis and Anticarcinogenesis Mechanisms by Delbert M. Shankel, Philip E. Hartman, Tsuneo Kada, Alexander Hollaender, Claire M. Wilson, Gregory Kuny.

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Bibliographic Details
Main Authors: Shankel, Delbert M. (Author), Hartman, Philip E. (Author), Kada, Tsuneo (Author), Hollaender, Alexander (Author), Wilson, Claire M. (Author), Kuny, Gregory (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 1986.
Edition:1st ed. 1986.
Series:Basic Life Sciences ; 39
Springer eBook Collection.
Subjects:
Organic chemistry.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Keynote Address
  • Carcinogens and Anticarcinogens
  • Activation and Inactivation of Mutagens and Carcinogens– –Part I
  • The Relation of Activation and Inactivation to Antimutagenic Processes
  • Cancer and Free Radicals
  • Cytochromes P-450 and the Activation and Inactivation of Mutagens and Carcinogens
  • Alteration of Mutagenic Potentials by Peroxidase, Catalase, and Superoxide Dismutase
  • Activation and Inactivation of Mutagens and Carcinogens– –Part II
  • Effects of Vitamins C and E on Carcinogen Formation and Action, and Relationship to Human Cancer
  • Modifiers of Endogenous Nitrosamine Synthesis and Metabolism
  • Glutathione Transferases and Carcinogenesis
  • Natural Environmental Antimutagens
  • Introduction: Natural Environmental Antimutagens
  • Antioxidants/Antimutagens in Foods
  • Role of Enzymes in Antimutagenes is of Human Saliva and Serum
  • Isolation and Identification of Higher Plant Agents Active in Antimutagenic Assay Systems: Glycyrrhiza glabra
  • Mechanism of Action of Antimutagens and Anticarcinogens
  • Interception of Toxic Agents/Mutagens/Carcinogens: Some of Nature’s Novel Strategies
  • Antimutagens and Their Modes of Action
  • Avoidance of Errors in Dna
  • Introduction: Avoidance of Spontaneously Occurring Errors in DNA
  • Introduction: Avoidance of Errors After DNA Damage
  • Alkylation and Oxidative Damages to DNA: Constitutive and Inducible Repair Systems
  • Molecular Mechanism of Adaptive Response to Alkylating Agents
  • Nucleotide Excision Repair Genes from the Yeast Saccharomyces cerevisiae
  • The Fixation of Errors
  • Introduction: Molecular Basis of Genomic Stability and Change
  • Genetic Analyses of the Roles of UmuDC and MucAB in Mutagenesis
  • Mechanisms of Spontaneous Mutagenesis: Clues from Altered Mutational Specificity in DNA Repair-Defective Strains
  • Genetics and Molecular Biology of Mammalian Cells– –Part I
  • Introduction: Comparative Responses to DNA Damage in Bacteria and Mammalian Cells
  • Inducible Cellular Responses to DNA Damage in Mammalian Cells
  • Single-Base Mutations Associated with Mouse Lymphomas
  • The Mouse Mutant “Wasted”: An Animal Model for Ataxia-Telangiectasia
  • Genetics and Molecular Biology of Mammalian Cells– –Part II
  • Introduction: Oxygen Metabolism, DNA Repair, and the Origin of Spontaneous Genetic Instability
  • Multiple Inducible Cytochromes P-450 in Yeast
  • DNA Repair Genes of Mammalian Cells
  • Genetic and Chemical Factors Affecting Chemical Mutagenesis in Cultured Mammalian Cells
  • Mechanisms of Carcinogenicity and Anticarcinogenicity––Part I
  • Mechanisms of Carcinogenicity and Anticarcinogenicity: Role of Dietary Components
  • Reducing the Genotoxic Damage in the Oral Mucosa of Betel Quid/Tobacco Chewers
  • The Concentration of Bile Acids in the Fecal Stream as a Risk Factor for Colon Cancer
  • Hormones and Dietary Factors Controlling Gene Activation and Expression in Carcinogenesis
  • Dietary Promoters and Antipromoters
  • Mechanisms of Carcinogenicity and Anticarcinogenicity– –Part II
  • A Mutagen Is a Mutagen, Not Necessarily a Carcinogen
  • DNA Repair and Replication in Xeroderma Pigmentosum and Related Disorders
  • Role of Intercellular Communication in Modifying the Consequences of Mutations in Somatic Cells
  • Mechanisms of Carcinogenicity and Anticarcinogenicity– –Part III
  • Genetic Aspects of Cancer Epidemiology
  • Protective Effects of Beta-Carotene Against Psoralen Phototoxicity: Relevance to Protection Against Carcinogenesis
  • Anticarcinogenic and Other Protective Effects of Dithiolthiones
  • Antioxidants as Antitumor Promoters
  • Future Directions for Research in Antimutagenesis and Anticarcinogenesis
  • Introduction: Future Directions for Research in Antimutagenesis and Anticarcinogenesis
  • Inhibitors of Mutagenesis and Their Relevance to Carcinogenesis
  • Population Consequences of Mutagenesis and Antimutagenesis
  • A Summary––And a Look Ahead
  • Poster Abstracts
  • Organizing Committee.

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