Dynamics and the Problem of Recognition in Biological Macromolecules

Dynamics and the Problem of Recognition in Biological Macromolecules edited by Oleg Jardetzky, Jean-François Lefèvre.

From within complex structures of organisms and cells down to the molecular level, biological processes all involve movement. Muscular fibers slide on each other to activate the muscle, as polymerases do along nucleic acids for replicating and transcribing the genetic material. Cells move and organi...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Jardetzky, Oleg (Editor), Lefèvre, Jean-François (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 1996.
Edition:1st ed. 1996.
Series:Nato Science Series A:, Life Sciences ; 288
Springer eBook Collection.
Subjects:
Biochemistry.
Biotechnology.
Animal anatomy.
Plant science.
Botany.
Animal physiology.
Biophysics.
Biological physics.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • 1. The Cooperative Substructure of Protein Molecules
  • 2. NMR Structures of Serine Proteinase Inhibitors LDTI and RBI, and Comparison with X-Ray Structures
  • 3. Solution Structure of the Long Neurotoxin LSIII with Possible Implications for Binding to the Acetylcholine Receptor
  • 4. NMR Studies of Enzyme-Substrate and Protein-Protein Interactions
  • 5. The Direct Determination of Protein Structure from Multidimensional NMR Spectra without Assignment: An Evaluation of the Concept
  • 6. Accuracy of Nuclear Magnetic Resonance Derived Molecular Structures: Quantitative Uncertainty Analysis of Distance Constraints
  • 7. What Limits Protein Folding
  • 8. Approaches to the Determination of More Accurate Cross-Relaxation Rates and the Effects of Improved Distance Constraints on Protein Solution Structures
  • 9. Protein Dynamics: From the Native to the Unfolded State and Back Again
  • 10. Insights into Protein Dynamics by NMR Techniques
  • 11. Heteronuclear Relaxation and the Experimental Determination of the Spectral Density Function
  • 12. How Conventional Antigens and Superantigens Interact with the Human MHC Class II Molecule HLA-DR1
  • 13. Simulating the Dynamics of the DNA Double Helix in Solution
  • 14. Developments in NMR Structure Determination of Nucleic Acids
  • 15. Solution Dynamics of the trp-Repressor Studied by NMR Spectroscopy
  • 16. A Refined NMR Solution Structure of the POU-Specific Domain of the Human Oct-1 Protein
  • 17. Applications of Multidimensional Solid-State NMR Spectroscopy to Membrane Proteins
  • 18. Conformation, Mobility, and Function of the N-Linked Glycan in the Adhesion Domain of Human CD2
  • Abstracts
  • Participants Photos
  • Author Index.

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