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|a 9781461511618
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|a 10.1007/978-1-4615-1161-8
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|a Androgens and Androgen Receptor
|h [electronic resource] :
|b Mechanisms, Functions, and Clini Applications /
|c edited by Chawnshang Chang.
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| 250 |
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|a 1st ed. 2002.
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| 264 |
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1 |
|a New York, NY :
|b Springer US :
|b Imprint: Springer,
|c 2002.
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| 300 |
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|a XIV, 503 p.
|b online resource.
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|a 1. Androgen Biosynthesis and Degradation -- 2. Structural and Functional Analysis of the Androgen Receptor -- 3. Signal Transduction Pathways Modulate Androgen Receptor Transcriptional Activity -- 4. Androgen Receptor Interacting Proteins Co-Activators and Co-Repressors -- 5. Nongenomic Androgen Action -- 6. The Role of 5?-Reductase in Prostate Disease and Male Pattern Baldness -- 7. Natural Products and Environmental Androgens/Antiandrogens -- 8. Androgens in Prostate Cancer and Benign Prostatic Hypoplasia -- 9. The Expanded Poly-Q Length Within AR and AR Coregulator A1B1 And Their Clinical Implications -- 10. Androgen Receptor with Expanded Poly-Q Length in SBMA (Kennedy Disease) -- 11. Androgen Insensivity Syndrome (Testicular Feminization) -- 12. Androgens in Immunology and Autoimmune Diseases -- 13. Androgens in Penile Development, Penile Erection and Erectile Dysfunction -- 14. Androgens and the Androgen Receptor in Male Sex Development and Fertility -- 15. Androgens and Brain Function: Behavioral Perspectives -- 16. Androgens, Skeletal Homeostasis, and Osteoporosis -- 17. Androgens and Coronary Artery Disease -- 18. Androgen Therapy in Nonendocrine Illnesses -- 19. Androgens and Androgen Receptor in Dermatology -- 20. Androgen Deficiency and Abnormality in Women.
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| 520 |
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|a Androgen Receptors is the most comprehensive and up to date volume on the topic, including discussions of the basic mechanisms of androgen-androgen receptor actions, their roles in the androgen-related diseases, and their potential clinical applications. Key topics covered include: -The discovery and cloning of the androgen receptor; -Androgen receptor coregulators; -Androgen related genes and their consensus DNA response elements; -Basic mechanism of action including functional analyses, cellular localization and phosphorylation studies; -Cross-talk to other signal transduction systems; -The recent connections of androgens to women's diseases, such as osteoporosis and ovarian cancer. This book is of interest to students, basic scientists, and clinicians as both a study guide and reference of research in the androgen field. It could also be used as an advanced level text in endocrinology, urology, OBGYN, or oncology.
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| 590 |
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|a Loaded electronically.
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| 590 |
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|a Electronic access restricted to members of the Holy Cross Community.
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| 650 |
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|a Veterinary medicine.
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| 650 |
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|a Cancer research.
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| 650 |
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|a Urology.
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| 650 |
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|a Gynecology .
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| 650 |
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|a Dermatology.
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| 690 |
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|a Electronic resources (E-books)
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| 700 |
1 |
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|a Chang, Chawnshang.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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| 710 |
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