Clinical Pharmacology of Anti-Epileptic Drugs Workshop on the Determination of Anti-Epileptic Drugs in Body Fluid II (WODADIBOF II) Held in Bethel, Bielefeld, Germany, 24 - 25 May, 1974

Clinical Pharmacology of Anti-Epileptic Drugs Workshop on the Determination of Anti-Epileptic Drugs in Body Fluid II (WODADIBOF II) Held in Bethel, Bielefeld, Germany, 24 - 25 May, 1974 / edited by H. Schneider, D. Janz, C. Gardner - Thorpe, H. Meinardi, A. L. Sherwin.

"He who is faithfully analysing ... epi­ lepsy is doing far more than studying epilepsy" Hughlings Jackson Modifying this well-known statement by Jackson, one could say today: "He who is faithfully analysing anti-epileptic drugs is doing far more than studying anti-epileptic drugs&quo...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Schneider, H. (Editor), Janz, D. (Editor), Gardner - Thorpe, C. (Editor), Meinardi, H. (Editor), Sherwin, A. L. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1975.
Edition:1st ed. 1975.
Series:Springer eBook Collection.
Subjects:
Pharmacology.
Pharmacy.
Medicine.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • A. Pharmacokinetics
  • Statistical Analysis of Pharmacokinetic Parameters in Epileptic Patients Chronically Treated with Anti-Epileptic Drugs
  • Clinical Pharmacokinetics in Monitoring Chronic Medication with AntiEpileptic Drugs
  • Drug Interactions at the Metabolic Level: A Reality in Drug Treatment of Epilepsy
  • B. Pharmacology of Anti-Epileptic Drugs
  • I. Phenytoin
  • Comparison of Gas-Chromatographic and Spectrophotometric Determinations of Phenytoin in Serum
  • Serum Levels of Phenytoin in Children
  • Problems in Controlled Anti-Epileptic Treatment with Phenytoin in Children
  • Longitudinal Studies of Serum Anti-Epileptic Drug Levels. Preliminary Observations: Interaction of Phenytoin and Primidone
  • Effect of Drug Therapy on the Metabolism of Phenytoin
  • II. Ethotoin
  • Plasma Concentrations of Ethotoin in Epileptic Patients
  • A Gas Chromatographic Method for the Determination of Ethotoin (3- Ethyl-5-Phenylhydantoin) in Human Plasma
  • III. Barbiturates
  • Some Problems Concerning the Quantitative Assay of Primidone and Its Metabolites
  • Determination of Hydroxymetabolites of Phenobarbitone and Phenytoin
  • The Effect of Psychotropic Drugs on Serum Anti-Epileptic Levels in Psychiatric Patients with Seizure Disorders
  • IV. Carbamazepine
  • Carbamazepine: An Attempt to Correlate Serum Levels with Anti-Epileptic and Side Effects
  • Pharmacokinetic Data o£ Carbamazepine and its Major Metabolites in Man
  • Pharmacokinetic Studies on Carbamezepine in Volunteers and in Epileptic Patients
  • A Preliminary Study of Serum Carbamazepine Levels in Healthy Subjects and in Patients with Epilepsy
  • Carbamazepine: The Influence of Other Anti-Epileptic Drugs on its Serum Level
  • Drug Interaction in Epileptic Patients
  • The Influence of Phenobarbitone and Phenytoin on Carbamazepine Serum Levels
  • V. Ethosuximide
  • Correlation of Serum Ethosuximide Levels with Clinical Effect
  • VI. Dipropylacetate
  • Less Usual Ways of Administering Anti-Epileptic Drugs
  • Enteric Coated Dipropylacetate (Depakine)
  • Analytical Data in Connection with the Clinical Use of Di-n-Propylacetate
  • VII. Clonazepam
  • Clinical Pharmacokinetic Experiences with Clonazepam
  • Pharmacokinetics of Clonazepam in Man and Laboratory Animals
  • C. Various Aspects (Varia)
  • Absorption and Protein Binding in Serum of Several Anti-Epileptic Drugs
  • Phenytoin and Phenobarbitone Levels in Human Brain and Cerebrospinal Fluid.
  • D. Quality Control and Standardization
  • Report on Worksheets Collected after WODADIBOF I
  • Results of a Phenytoin Quality Control Scheme
  • The Development of a Matrix Reference Standard for Anti-Epileptic Analysis
  • E. Methodology of Determination
  • Comparison of Methods for Determination of Drugs in Serum and Plasma
  • Application of a Nitrogen-Specific Detector for the Gas Chromatographic Determination of Phenytoin, Primidone and Phenobarbitone in 20 µl Serum.
  • Consecutive Determination of the Levels of Twelve Anti-Epileptic Drugs in Blood and Cerebrospinal Fluid
  • Evaluation of an Experimental Homogeneous Enzyme Immuno-Assay for the Quantitation of Phenytoin and Phenobarbitone in Serum or Plasma
  • F. Dictionary of Anti-Epileptic Drug Synonyms, Chemical Names and Nonproprietary Names
  • F. Dictionary of Anti-Epileptic Drug Synonyms, Chemical Names and Nonproprietary Names.

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