Viral Cytopathology Cellular Macromolecular Synthesis and Cytocidal Viruses Including a Cumulative Index to the Authors and Major Topics Covered in Volumes 1–19 / edited by Heinz Fraenkel-Conrat, Robert R. Wagner.

The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and numbering, has probably reached that stage at which relatively few new-truly new-viruses will be d...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Fraenkel-Conrat, Heinz (Editor), Wagner, Robert R. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 1984.
Edition:1st ed. 1984.
Series:Comprehensive Cytopathology ; 19
Springer eBook Collection.
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Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • 1 Cytopathic Effects of Viruses: A General Survey
  • 1. Defining the Problem
  • 2. Historical Background
  • 3. Viral Cytopathology: General Principles
  • 4. Specific Cytopathic Viruses: An Overview
  • 5. Some Subcellular Targets of Pathogenic Viruses
  • 6. Summary
  • 7. References
  • 2 Transcription by RNA Polymerase II
  • 1. Introduction
  • 2. Polymerase II Control Regions: In Vivo
  • 3. Polymerase II Promoters: In Vitro
  • 4. RNA Polymerase II and Factors
  • 5. Closing Comments
  • 6. References
  • 3 Regulation of Eukaryotic Translation
  • 1. Introduction
  • 2. The Rate-Limiting Step in Translation
  • 3. Functional Domains in Messenger RNA
  • 4. Initiation of Translation
  • 5. Role of Initiation Factors in Binding of mRNA
  • 6. Translational Control by mRNA Competition
  • 7. Translational Control by Regulation of eIF-2 Activity
  • 8. Translational Regulation by Other Means
  • 9. Parameters Determining Translational Efficiency of an mRNA Species
  • 10. References
  • 4 Picornavirus Inhibition of Host Cell Protein Synthesis
  • 1. Introduction and Scope
  • 2. Properties of Inhibition of Host Cell Protein Synthesis by Poliovirus
  • 3. Proposed Models for Inhibition
  • 4. Initiation Factors
  • 5. Cap Recognition Activity
  • 6. Polioviral Mediator of Host Cell Shut-off
  • 7. Other Picornaviruses
  • 8. Other Viruses That May Utilize Mechanisms Similar to Poliovirus
  • 9. Concluding Remarks
  • 10. References
  • 5 Rhabdovirus Cytopathology: Effects on Cellular Macromolecular Synthesis
  • 1. Introduction
  • 2. Properties of Rhabdoviruses: A Brief Survey
  • 3. Cellular Responses to Rhabdovirus Infection
  • 4. Protein Synthesis Inhibition by Vesicular Stomatitis Virus
  • 5. VSV Inhibition of Cellular Nucleic Acid Synthesis
  • 6. Summary
  • 7. References
  • 6 Adenovirus Cytopathology
  • 1. Introduction
  • 2. Adenovirus—Mammalian Cell Interactions
  • 3. Effects of Adenovirus Infection on Cellular DNA Metabolism
  • 4. Cellular RNA Metabolism in Adenovirus-Infected Cells
  • 5. Selective Translation of Viral mRNA in Productively-Infected Cells
  • 6. Summary and Conclusions
  • 7. References
  • 7 The Effects of Herpesviruses on Cellular Macromolecular Synthesis
  • 1. Introduction
  • 2. Early Studies
  • 3. Effects on DNA Synthesis
  • 4. Effects on RNA Synthesis
  • 5. Effects on Protein Synthesis
  • 6. Other Herpesviruses
  • 7. Mechanisms
  • 8. Conclusion
  • 9. References
  • 8 Poxvirus Cytopathogenicity: Effects on Cellular Macromolecular Synthesis
  • 1. Introduction
  • 2. Poxvirus Cytopathogenicity
  • 3. Concluding Remarks
  • 4. References
  • 9 Reovirus Cytopathology: Effects on Cellular Macromolecular Synthesis and the Cytoskeleton
  • 1. Introduction
  • 2. Reovirus Effects on Host Cell DNA Synthesis
  • 3. Reovirus Effects on Host Cell RNA and Protein Synthesis
  • 4. Reovirus Effects on Cytoskeletal Organization
  • 5. Summary
  • 6. References
  • 10 Inhibition of Host Cell Macromolecular Synthesis following Togavirus Infection
  • 1. Introduction
  • 2. Acute Infection by Alphaviruses in Vertebrate Cell Cultures
  • 3. Chronic and Persistent Infection by Alphaviruses in Vertebrate Cell Cultures
  • 4. Infections by Flaviviruses in Vertebrate Cell Cultures
  • 5. Infection by Togaviruses in Invertebrate Cell Cultures
  • 6. Concluding Remarks
  • 7. References
  • Cumulative Contents
  • Cumulative Author Index
  • Cumulative Subject Index.