Advances in Prostaglandin and Leukotriene Research Basic Science and New Clinical Applications / edited by Bengt Samuelsson, Rodolfo Paoletti, Giancarlo Folco, E. Granström, S. Nicosia.

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Samuelsson, Bengt (Editor), Paoletti, Rodolfo (Editor), Folco, Giancarlo (Editor), Granström, E. (Editor), Nicosia, S. (Editor)
Format: eBook
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2001.
Edition:1st ed. 2001.
Series:Medical Science Symposia Series, 16
Springer eBook Collection.
Subjects:
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.

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245 1 0 |a Advances in Prostaglandin and Leukotriene Research  |h [electronic resource] :  |b Basic Science and New Clinical Applications /  |c edited by Bengt Samuelsson, Rodolfo Paoletti, Giancarlo Folco, E. Granström, S. Nicosia. 
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505 0 |a I Lipdxygenases and Leukotriene Biosynthesis -- 1. Phosphorylation and Activation of 5-Lipoxygenase by P38 Kinase-Activated MAPKAP Kinases -- 2. 5-Lipoxygenase and the Nucleus: Where, When, How, and Why? -- 3. Calcium Binding Site of 5-Lipoxygenase -- 4. Regulation of Cellular 5-Lipoxygenase Activity by Glutathione Peroxidases -- 5. Novel Aspects Related to Biosynthesis and Biological Actions of Hepoxilins: Interrelationship with Phospholipid Hydro-Peroxide Glutathione Peroxidase (PHGPx) -- 6. Transcriptional Regulation of the Human Leukotriene C4 Synthase Promoter -- 7. Localization and Translocation of Enzymes Involved in Leukotriene Biosynthesis -- II Cyclooxygenases and Prostaglandin Biosynthesis -- 8. Regulation of COX-2 Expression in Fibroblasts, Osteoblasts, Mast Cells, and Macrophages -- 9. Antimicroinflammatory Lipid Signals from Vascular Cyclooxygenase-2: A Novel Mechanism for NSAID and N-3 PUFA Therapeutic Actions -- 10. Substrate Interactions in the Cyclooxygenase-1 Active Site -- 11. Mutation of the Human Prostacyclin Synthase Gene -- 12. Structure and Function of Two Distinct Types of Prostaglandin D Synthase -- 13. Roles of Prostaglandin F Synthase -- 14. Differential Effects of Nitric Oxide on Cyclooxygenase 1 and 2 Activities in Cultured Cells -- III Phospholipase A2 -- 15. On the Functional Diversity of Secreted Phospholipases A2: Cloning of Novel Mammalian and HIV-1 Antiviral Properties -- 16. Regulation of Cytosolic Phospholipase A2 by Phosphorylation -- IV Cytochrome P450 Archidonate Metabolites -- 17. Synthesis and Function of 20-Hydroxyeicosatetraenoic Acid in the Kidney -- V Receptors -- 18. Altered Bronchodilation and Pulmonary Inflammation in Prostanoid EP2 Receptor Knockout Mice -- 19. Induction of Prostaglandin I2 Receptor in Murine Osteoblastic Cell -- 20. BLT2, a Second Leukotriene B4 Receptor -- 21. Upregulation of Cysteinyl-Leukotriene 1 Receptor Expression by Interleukin-5 in Human Leukocytes -- 22. Physiological and Pathophysiological Roles of Prostanoids; Lessons from Receptor-Knockout Mice for Clinical Applications -- 23. Multiple G-Protein Coupling of Chimeric Prostacyclin/Prostaglandin D2 Receptors -- VI Eicosanoids and Neuroscience -- 24. An Unusual Nicotinic Acetylcholine Receptor Activates the 8-Lipoxygenase Pathway in Aplysia Neurons -- VII Cardiovascular System -- 25. Neutrophil-Endothelial Cell Interaction: A Multidirectional Cross-Talk in Leukotriene Generation -- 26. Cyclooxygenase in the Lamb Ductus Arteriosus: Developmental Changes and Upregulation -- 27. Co-Localization of Prostacyclin (PGI2)-Synthase and Caveolin-1 in Endothelial Cells Underscores New Roles of PGI2 In Angiogenesis -- VIII Respiratory System -- 28. Leukotriene C4 Synthase Gene Polymorphism in Severe Asthma -- IX Inflammation -- 29. Anti-Inflammatory Levels of Aspirin and Salicylate Inhibit Integrin-Dependent Human Neutrophil Aggregation and PMN Influx in COX2- and NFkB(P105)- Knockout Mice -- 30. Antipyretic Action of Acetaminophen: Inhibition of the Cyclooxygenase Activity of Endothelial Cells Treated with IL-1 -- 31. Leukotriene-Mediated Alteration of Endothelial Barrier Function -- 32. GI and Cardiovascular Profiles of New NSAIDs: Selective COX-2 Inhibitors and NO-NSAIDs -- 33. NO-Releasing NSAIDs Modulate Cytokine Secretion -- 34. Potent Inhibitory Effects of a NO-NSAID (Flurbiprofen Nitroxybutylester) on Bone Resorption in Vitro and in Vivo -- X Cancer -- 35. Lipid Peroxidation and Cyclooxygenase-2 Activity in Human Hepatocellular Carcinoma Cell Lines with and without Multiple Drug Resistance: Correlation with Cell Growth -- 36. Pulmonary Prostacyclin Synthase Overexpression Improves Survival Following Butylated Hydroxytoluene Exposure -- XI Isoprostanes -- 37. Reactive Products of the Isoprostane Pathway: Isoketals and Cyclopentenone A2/J2-Isoprostanes -- 38. Increased Isoprostane 8-epi-PGF2A in Statin-Induced Myopathy. 
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650 0 |a Biochemistry. 
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