Advances in Eicosanoid Research edited by C.N. Serhan, H.D. Perez.

Over the last few years, we have witnessed tremendous progress in the field of eicosanoids and their therapeutic applications. Receptor an­ tagonists for leukotrienes have been tested as anti-inflammatories and are on the market as a treatment for asthma. Receptor agonists for pro­ stacyclin are bei...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Serhan, C.N (Editor), Perez, H.D (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2000.
Edition:1st ed. 2000.
Series:Ernst Schering Foundation Symposium Proceedings, 31
Springer eBook Collection.
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Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • 1 The Mechanism of Action of Anti-Inflammatory Drugs
  • 2 Human Group-V Phospholipase-A2 Expression in Pichia pastoris and Its Role in Eicosanoid Generation
  • 3 Fatty-Acid Substrate Interactions with Cyclooxygenases
  • 4 Structure, Function and Inhibition of Cyclooxygenases
  • 5 Leukotriene-A4 Hydrolase: Probing the Active Sites and Catalytic Mechanisms by Site-Directed Mutagenesis
  • 6 The Regulation of Cyclooxygenase-1 and -2 in Knockout Cells and Cyclooxygenase and Fever in Knockout Mice
  • 7 Leukotriene-B4 Receptor and Signal Transduction
  • 8 Lipoxins, Aspirin-Triggered 15-epi-Lipoxin Stable Analogs and Their Receptors in Anti-Inflammation: a Window for Therapeutic Opportunity
  • 9 Lipoxin-Stable Analogs: Potential Therapeutic Downregulators of Intestinal Inflammation
  • 10 The Role of Eicosanoids in Tumor Growth and Metastasis
  • Previous Volumes Published in this Series.