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|a 9781489907271
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|a 10.1007/978-1-4899-0727-1
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|a (DE-He213)978-1-4899-0727-1
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|a Prostaglandins, Leukotrienes, Lipoxins, and PAF
|h [electronic resource] :
|b Mechanism of Action, Molecular Biology, and Clinical Applications /
|c edited by J. Martyn Bailey.
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| 246 |
3 |
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|a Proceedings of the XIth International Washington Spring Symposium at the George Washington University, held in Washington, D.C., May 13-17, 1991
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| 250 |
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|a 1st ed. 1991.
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| 264 |
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1 |
|a New York, NY :
|b Springer US :
|b Imprint: Springer,
|c 1991.
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| 300 |
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|a XI, 461 p.
|b online resource.
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| 336 |
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|b txt
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| 490 |
1 |
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|a Gwumc Department of Biochemistry and Molecular Biology Annual Spring Symposia
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| 490 |
1 |
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|a Springer eBook Collection
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| 505 |
0 |
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|a I — Molecular Biology and Enzymology of Prostaglandins and Leukotrienes -- 1. Translational Control of Prostaglandin Synthase by Growth Factors and Glucocorticoids -- 2. Two Types of Arachidonate 12-Lipoxygenase Demonstrated by Enzymological and Molecular Immunological and Molecular Biological Studies -- 3. A Model for the Transcriptional Regulation of a Mouse PGH Synthase Gene -- 4. Catalytic Properties and Reaction Mechanism of 5-Lipoxygenase -- 5. Cloning, Expression and Site-Directed Mutagenesis of the cDNA for Human Placental NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase -- 6. Regulation of Cyclooxygenase Gene Expression in Vascular Endothelial Cells -- 7. Structure-Function Studies and Physiological Roles of Eicosanoids Metabolized by Cytochrome P450 ?-Hydrolases -- 8. Multiple Cyclooxygenases: Cloning of a Mitogen Inducible Form -- 9. Amino Acids Essential to Catalysis by Prostaglandin Endoperoxide Synthase -- 10. Allene Oxide Biosynthesis and Metabolism -- 11. Lipoxygenase, Cyclooxygenase and Leukotriene A4 Hydrolase: Quantitative Polymerase Chain Reaction and Expression Studies -- II — Regulatory Mechanisms in Eicosanoid Release and Metabolism -- 12. Annexins and Signal Transduction -- 13. Structural and Functional Properties of Mammalian Group III Cytosolic Phospholipases A2 -- 14. Regulation of Plasma Membrane Phospholipase A2 Activity by Phosphorylation/Dephosphorylation: Is Glucocorticoid Action Mediated by Induction of Protein Phosphatase? -- 15. Eicosanoid/Signal Transduction Interactions: Evidence of Two Induced Pathways of Phosphoinositide Biosynthesis by LTB4 in Cultured Human Epidermal Cells -- 16. Prostaglandyl-Inositol Cyclic-Phosphate, A New Second Messenger -- 17. Incorporation of Hydroxyeicosatetraenoic Acids into Phospholipid Signalling Pathways -- 18. The Purification of Two Intracellular Phospholipase A2’s and the Effects of Phopholipase A2 Activating Protein and Mellitin on Their Activities -- 19. Differential Activation of Phospholipase A2 Activity and Prostacyclin Production in Rat Vascular Smooth Muscle Cells and Cardiomyocytes -- III — Cardiovascular Pulmonary Interactions of Prostaglandins, Prostacyclins and Leukotrienes -- 20. Thromboxane A2/Prostaglandin H2 Receptors: A Growing Family of Receptor Subtypes -- 21. The Regulation of Prostacyclin Secretion in Endothelial Cells -- 22. Metabolism of Arachidonic Acid by Purified Lung Epithelial Cells -- 23. Recovery of Human Tracheal Cell Epithelial Cell Cyclooxygenase Following Inactivation -- 24. Aortic Microsomal Prostacyclin Synthesis During Diet Induced Hypercholesterolemia -- 25. Activation of Protein Kinase C Regulates LTB4 Receptor on Guinea Pig Eosinophils -- IV — Recent Advance in Paf Metabolism and Function -- 26. Novel Neutrophil Agonists: Oxidatively-Fragmented Phosphatidylcholines -- 27. Specific Binding of Tritium-Labeled Platelet-Activating Factor to Human Mononuclear Leukocyte Membranes: A Third Putative Receptor of Platelet-Activating Factor -- 28. Tyrosine Kinase Phosphorylation in Human Neutrophil Activation by PAF and Other Agonists -- 29. Platelet-Activating Factor (PAF) Receptor in Brain and Signal Transduction in Neurons -- V — Immune Reactions, Cancer and Inflammatory Processes -- 30. Influence of PGE2 and LTB4 on CD8+ Thymocytes -- 31. Modulation of Cytokine Gene Expression by LTB4 and PAF: Transcriptional and Post-Transcriptional Regulation -- 32. Hepoxilin A3 Induces Vascular Permeability in the Skin -- 33. Lipoxygenase Metabolism in the Regulation of Hematopoiesis -- 34. Lipid Bodies: Structurally Distinct, Non-Membranous Intracellular Sites of Eicosanoid Formation -- 35. Tumor Prostaglandins and Estrogen Receptors: Prediction of Survival in Patients with Early Breast Cancer -- VI — Clinical and Pharmacological Applications of Eicosanoids -- 36. Lipid Mediators in Transplantation Reperfusion Injury, Acute Rejection and Accelerated Transplant Atherosclerosis -- 37. Pharmacological Profile, Pharmacokinetics and Biotransformation of the 5-Lipoxygenase Inhibitor FLM 5011 -- 38. Prostaglandin H Synthase: Perturbation of the Tyrosyl Radical as a Probe of Anti-Cyclooxygenase Agents -- 39. Selective Incorporation of HETEs into Epidermal Phospholipids -- 40. Lipoxin Generation in Human Whole Blood: Monitoring by Electron-Capture NICI/GC/MS -- 41. Therapeutic Aspects of Leukotriene Antagonists and Inhibitors -- 42. Tolerance to Cardiac Grafts Following Intra-Graft Infusion of 16,16 Dimethyl PGE2.
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| 590 |
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|a Loaded electronically.
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| 590 |
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|a Electronic access restricted to members of the Holy Cross Community.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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0 |
|a Biochemistry.
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| 690 |
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|a Electronic resources (E-books)
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| 700 |
1 |
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|a Bailey, J. Martyn.
|e editor.
|4 edt
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|a SpringerLink (Online service)
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| 830 |
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|a Gwumc Department of Biochemistry and Molecular Biology Annual Spring Symposia
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| 830 |
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|a Springer eBook Collection.
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