Cardiac Energetics Basic Mechanisms and Clinical Implications

Cardiac Energetics Basic Mechanisms and Clinical Implications / edited by R. Jacob, Hanjoerg Just, C. Holubarsch.

Assessment of cardiac energetics at the level of ATP-synthesis, chemomechanical energy transformation and whole organ dynamics as a function of haemodynamic load, ventricular configuration and oxygen- and substrates supply is basic to understanding cardiac function under physiological and pathophysi...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Jacob, R. (Editor), Just, Hanjoerg (Editor), Holubarsch, C. (Editor)
Format: eBook
Language:English
Published: Heidelberg : Steinkopff : Imprint: Steinkopff, 1987.
Edition:1st ed. 1987.
Series:Springer eBook Collection.
Subjects:
Cardiology.
Human physiology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • I. Cardiac energetics as related to basic mechanisms and mechanical conditions
  • The mechanism of muscle contraction. Biochemical, mechanical, and structural approaches to elucidate cross-bridge action in muscle
  • Energetics studies of muscles of different types
  • High energy phosphate of the myocardium: Concentration versus free energy change
  • Cardiac basal and activation metabolism
  • Mechanical determinants of myocardial energy turnover
  • Cardiac energetics and the Fenn effect
  • Cardiac energetics: significance of mitochondria
  • Heat production and oxygen consumption following contraction of isolated rabbit papillary muscle at 20°C
  • Regulation of heart creatine kinase
  • Effect of creatine depletion on myocardial mechanics
  • ATPase activity of intact single muscle fibres of Xenopus laevis is related to the rate of force redevelopment after rapid shortening
  • II. Cardiac energetics as related to ontogenesis, chronic myocardial transformation and inotropic interventions
  • Developmental differences in myocardial ATP metabolism
  • The effects of acute and chronic inotropic interventions on tension independent heat of rabbit papillary muscle
  • Chronic cardiac reactions. I. Assessment of ventricular and myocardial work capacity in the hypertrophied and dilated ventricle
  • Chronic cardiac reactions. II. Mechanical and energetic consequences of myocardial transformation versus ventricular dilatation in the chronically pressure-loaded heart
  • Chronic cardiac reactions. III. Factors involved in the development of structural dilatation
  • Chronic cardiac reactions. IV. Effect of drugs and altered functional loads on cardiac energetics as inferred from myofibrillar ATPase and the myosin isoenzyme population
  • Ca-independent regulation of cardiac myosin
  • Implications of myocardial transformation for cardiac energetics
  • Myocardial energetics and diastolic dimensions of the heart in experimental hypertension
  • Myocardial contractility and left ventricular myosin isoenzyme pattern in cardiac hypertrophy due to chronic volume overload
  • Decreased L-carnitine transport in mechanically overloaded rat hearts
  • New aspects of excitation-contraction coupling in cardiac muscle: Two types of Ca++ entry promotion with and without involvement of cyclic AMP and Mg++ ions
  • Energetic aspects of inotropic interventions in rat myocardium
  • III. Cardiac energetics in hypoxia and ischaemia
  • Mechanics of rat myocardium revisited: Investigations of ultra-thin cardiac muscles under high energy demand
  • Changes in myocardial distensibility in rat papillary muscle: Fibrosis, KCl contracture, hypoxic contracture, oxygen and glucose deficiency contracture, and experimental tetanus
  • Ultrastructural observations on the effects of different substrates on ischaemic contracture in global subtotal ischaemia in the rat heart
  • Diastolic relaxation abnormalities during ischaemia and their association with high energy phosphate depletion, intracellular pH and myocardial blood flow
  • Inotropic changes in ischaemic and non-ischaemic myocardium and arrhythmias within the first 120 minutes of coronary occlusion in pigs
  • Phosphocreatine and adeninenucleotides in postasphyxial hearts with normal basal function and normal oxygen demand
  • Changes in cardiovascular adrenoceptor response in rats subsequent to myocardial infarction
  • Cardioprotection by anti-ischaemic and cytoprotective drugs
  • Myocardial protection by antioxidant during permanent and temporary coronary occlusion in dogs
  • Promising reduction of ventricular fibrillation in experimentally induced heart infarction by antioxidant therapy
  • IV. Cardiac energetics in human heart: Clinical implications
  • Atrial and ventricular isomyosin composition in patients with different forms of cardiac hypertrophy
  • Heterogeneous regulatory changes in cell surface membrane receptors coupled to a positive inotropic response in the failing human heart
  • Acute and chronic changes of myocardial energetics in the mammalian and human heart
  • Cardiac energetics in clinical heart disease
  • Influence of phosphodiesterase inhibition on myocardial energetics in dilative cardiomyopathy
  • Predicting postoperative haemodynamics in valve patients.

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