The Statistics of Gene Mapping

The Statistics of Gene Mapping by David Siegmund, Benjamin Yakir.

Gene mapping is used in experimental genetics to improve the hardiness or productivity of animals or plants of agricultural value, to explore basic mechanisms of inheritance, or to study animal models of human inheritance. In human populations it is used as a first step to identify genes associated...

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Bibliographic Details
Main Authors: Siegmund, David (Author), Yakir, Benjamin (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2007.
Edition:1st ed. 2007.
Series:Statistics for Biology and Health,
Springer eBook Collection.
Subjects:
Human genetics.
Bioinformatics.
Statistics .
Computer simulation.
Animal genetics.
Biomathematics.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Background and Preparations
  • Background in Statistics
  • to Experimental Genetics
  • Fundamentals of Genetics: Inbreeding, Recombination, Random Mating, and Identity by Descent
  • Experimental Genetics
  • Testing for Linkage with a Single Marker
  • Whole Genome Scans: The Significance Level
  • Statistical Power and Confidence Regions
  • Missing Data and Interval Mapping
  • Advanced Topics
  • Human Genetics
  • Mapping Qualitative Traits in Humans Using Affected Sib Pairs
  • Admixture Mapping
  • Mapping Complex and Quantitative Traits with Data from Human Pedigrees
  • Association Studies
  • Inferring Haplotypes from Genotypes and Testing Association.

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