Obesity and Breast Cancer The Role of Dysregulated Estrogen Metabolism / by Kristy A. Brown, Evan R. Simpson.
Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-depend...
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