Obesity and Breast Cancer The Role of Dysregulated Estrogen Metabolism

Obesity and Breast Cancer The Role of Dysregulated Estrogen Metabolism / by Kristy A. Brown, Evan R. Simpson.

Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-depend...

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Bibliographic Details
Main Authors: Brown, Kristy A. (Author), Simpson, Evan R. (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2014.
Edition:1st ed. 2014.
Series:SpringerBriefs in Cancer Research,
Springer eBook Collection.
Subjects:
Cancer research.
Metabolic diseases.
Enzymology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Introduction
  • Estrogens, adiposity and the menopause
  • The link between obesity and breast cancer: Epidemiological evidence
  • Adipose-derived and obesity-related factors and breast cancer
  • Estrogen biosynthesis
  • Therapies aimed at breaking the linkage between obesity and breast cancer
  • Conclusions.

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