Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules The Shape of Organic Synthesis to Come

Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules The Shape of Organic Synthesis to Come / edited by Yuichi Kobayashi.

This book describes cutting-edge organic syntheses of biologically active compounds, isolation of pharmaceutically promising compounds from microorganisms, drug design, and progress on chemical biology. Synthetic strategy and tactics are summarized for super-carbon chain compounds, antitumor polycyc...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Kobayashi, Yuichi (Editor)
Format: eBook
Language:English
Published: Singapore : Springer Singapore : Imprint: Springer, 2019.
Edition:1st ed. 2019.
Series:Springer eBook Collection.
Subjects:
Organic chemistry.
Medicinal chemistry.
Pharmacy.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • 1. Microbial Fraction Library: A Screening Source for Drug Discovery
  • 2. Efficient Total Synthesis of Ōmura Natural Products
  • 3. Enantioselective Total Synthesis of the Antitumor Polycyclic Natural Products, FR182877 and Taxol
  • 4. Synthetic Approaches on the Pluramycin-class Antibiotics
  • 5. Recent Progress Toward the Total Synthesis of Duocarmaycins A and SA, Yatakemaycin, and PDE-I and –II
  • 6. Structure-Activity Relationship Studies of Maitotoxin Based on Chemical Synthesis
  • 7. Substitution of Allylic Picolinates with Various Copper Reagents and Synthetic Applications
  • 8. Total Synthesis of Ingenol
  • 9. Strategies for Synthesis of Anti-inflammatory Metabolites of Unsaturated Fatty Acids
  • 10. Biosynthesis, biological functions, and receptors of leukotriene B4 and 12(S)-hydroxyheptadecatrienoic acid
  • 11. Synthesis of classical/non-classical hybrid cannabinoids and related compounds
  • 12. Exploring bioactive marine natural products and identification of their molecular targets
  • 13. Target protein chemical modification
  • 14. Target Identification of Bioactive Compounds by Photoaffinity Labeling Using Diazido Probes.

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