Tumor-Induced Immune Suppression Mechanisms and Therapeutic Reversal

Tumor-Induced Immune Suppression Mechanisms and Therapeutic Reversal / edited by Dmitry I. Gabrilovich, Arthur Andrew Hurwitz.

Tumor Induced Immune Suppression: Mechanisms and Therapeutic Reversal focuses on the critical question of tumor biology: "Why can tumors escape immune system control?" It also addresses one of the most important problems within the field of clinical oncology: the lack of efficient cancer v...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Gabrilovich, Dmitry I. (Editor), Hurwitz, Arthur Andrew (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2008.
Edition:1st ed. 2008.
Series:Springer eBook Collection.
Subjects:
Cancer research.
Immunology.
Medical microbiology.
Cell biology.
Human genetics.
Developmental biology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Immune-Suppressive Mechanisms and Cancer: Understanding the Implications, Paradoxes, and Burning Questions
  • Mechanisms of Tumor-Associated T-Cell Tolerance
  • Contribution of B7-H1/PD-1 Co-inhibitory Pathway to T-Cell Dysfunction in Cancer
  • Regulatory T Cells in Cancer
  • Cancer-Induced Signaling Defects in Antitumor T Cells
  • Immunobiology of Dendritic Cells in Cancer
  • Macrophages and Tumor Development
  • Myeloid-Derived Suppressor Cells in Cancer
  • Signaling Pathways in Antigen-Presenting Cells Involved in the Induction of Antigen-Specific T-Cell Tolerance
  • Arginine Availability Regulates T-Cell Function in Cancer
  • Protein–Glycan Interactions in the Regulation of Immune Cell Function in Cancer: Lessons from the Study of Galectins-1 and -3
  • Role of Reactive Oxygen Species in T-Cell Defects in Cancer
  • Tumor Stroma and the Antitumor Immune Response.

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