Bone Metastases A translational and Clinical Approach

Bone Metastases A translational and Clinical Approach / edited by Vassilios Vassiliou, Edward Chow, Dimitrios Kardamakis.

The second edition of this book serves both as an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume describes the molecular and cellular mechanisms involved in the formation of bone metastases, presents th...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Vassiliou, Vassilios (Editor), Chow, Edward (Editor), Kardamakis, Dimitrios (Editor)
Format: eBook
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
Edition:2nd ed. 2014.
Series:Cancer Metastasis - Biology and Treatment, 21
Springer eBook Collection.
Subjects:
Cancer research.
Oncology  .
Medicine.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Preface. I Fundamental Concepts
  • Pathophysiology of metastatic bone disease
  • Bone metastases: epidemiology, clinical picture, SREs and prognosis
  • Pain in bone metastases: types and mechanisms. II Investigations Of Bone Metastases
  • Radiological evaluations: radiography, CT, MRI.- Nuclear medicine imaging modalities: bone scintigraphy, PET-CT, SPECT.- Bone turnover markers
  • New omics approaches for bone metastases. III Therapeutic Management.- Analgesic treatment for bone mets
  • Radiotherapy: external beam and radio-surgery
  • Radionuclide therapy
  • Bisphosphonates
  • New targeted therapies for bone metastases
  • Chemotherapy and hormone therapy
  • HIFU/Radioablation
  • Neuropathic bone metastases
  • Spinal cord compression and cauda equina compression
  • Pathological and impending fracture
  • Re-irradiation
  • Bone metastases in elderly patients
  • Management of metastatic bone disease in the elderly with bisphosphonates and RANKL inhibitors: effectiveness and safety. IV Assesment of Therapeutic Response
  • Radiological and nuclear medicine imaging modalities.- Clinical assessment measures
  • Outcome measures in bone metastases clinical trials
  • Quality of life in patients suffering from metastatic skeletal disease. V Cost of Managing Metastatic Bone Disease
  • Cost effectiveness of treatment modalities for bone metastases
  • Index.

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