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|a 9783030201869
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|a 10.1007/978-3-030-20186-9
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|a (DE-He213)978-3-030-20186-9
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| 245 |
1 |
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|a The Nociceptin/Orphanin FQ Peptide Receptor
|h [electronic resource] /
|c edited by Mei-Chuan Ko, Girolamo Caló.
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| 250 |
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|a 1st ed. 2019.
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| 264 |
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1 |
|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2019.
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| 300 |
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|a X, 417 p. 78 illus., 21 illus. in color.
|b online resource.
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|a Handbook of Experimental Pharmacology,
|x 0171-2004 ;
|v 254
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| 490 |
1 |
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|a Springer eBook Collection
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| 505 |
0 |
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|a PART I. The N/OFQ-NOP Receptor System -- 1. The History of N/OFQ and the NOP Receptor -- 2. NOP-Targeted Peptide Ligands -- 3. NOP-Targeted Nonpeptide Ligands -- 4. Pharmacological Assays for Investigating the NOP Receptor -- 5. Electrophysiological Actions of N/OFQ -- 6. NOP Receptor Signaling Cascades -- 7.Regulation of the Genes Encoding the ppN/OFQ and NOP Receptor -- PART II. Biological Actions of NOP Ligands -- 8.NOP-Related Mechanisms in Pain and Analgesia -- 9. NOP-Related Mechanisms in Substance Use Disorders -- 10. NOP Receptor Ligands and Parkinson’s Disease -- 11. NOP Ligands for the Treatment of Anxiety and Mood Disorders -- 12. The Nociceptin/Orphanin FQ System and the Regulation of Memory -- 13. N/OFQ-NOP System in Food Intake -- 14. N/OFQ-NOP System in Peripheral and Central Immunomodulation -- 15. N/OFQ-NOP System and Airways -- 16. Effects of NOP-Related Ligands in Nonhuman Primates -- PART III. First Clinical Studies with NOP Ligands -- 17. Nociceptin/Orphanin FQ and Urinary Bladder -- 18. Cebranopadol: A Novel First-in-Class Potent Analgesic Acting via NOP and Opioid Receptors -- 19. Therapeutic Approaches for NOP Receptor Antagonists in Neurobehavioral Disorders: Clinical Studies in Major Depressive Disorder and Alcohol Use Disorder with BTRX-246040 (LY2940094) -- 20. Correction to: Electrophysiological Actions of N/OFQ.
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| 520 |
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|a The aim of this book is not only to introduce readers with a broad spectrum of biological actions of the NOP receptor, but also to feature a detailed look at the N/OFQ-NOP receptor system, medicinal chemistry, pharmacology, and clinical data of NOP-targeted ligands. This special volume book - for the first time focusing on the NOP receptor - is designed to serve as a useful reference, stimulate more research on the N/OFQ-NOP receptor system, and lead to more development of NOP-related ligands for several therapeutic applications.
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| 590 |
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|a Loaded electronically.
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| 590 |
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|a Electronic access restricted to members of the Holy Cross Community.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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0 |
|a Neurosciences.
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| 650 |
|
0 |
|a Anesthesiology.
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| 650 |
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0 |
|a Pain medicine.
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| 650 |
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0 |
|a Psychopharmacology.
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| 690 |
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|a Electronic resources (E-books)
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| 700 |
1 |
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|a Ko, Mei-Chuan.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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| 700 |
1 |
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|a Caló, Girolamo.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 830 |
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0 |
|a Handbook of Experimental Pharmacology,
|x 0171-2004 ;
|v 254
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| 830 |
|
0 |
|a Springer eBook Collection.
|
| 856 |
4 |
0 |
|u https://holycross.idm.oclc.org/login?auth=cas&url=https://doi.org/10.1007/978-3-030-20186-9
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