Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines

Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines edited by Manmohan Singh.

Development of new-generation vaccines is now more challenging than ever, as identifying, purifying and evaluating vaccine antigens is a complex undertaking. Most importantly, once the relevant antigens have been identified, key focus then shifts to the development of suitable delivery systems and f...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Singh, Manmohan (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 2013.
Edition:1st ed. 2013.
Series:Springer eBook Collection.
Subjects:
Immunology.
Medical microbiology.
Vaccines.
Pharmaceutical technology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Critical parameters that govern the optimization of vaccine formulations
  • Development of Biophysical assays to better understand vaccine formulation stability
  • Rational design of vaccine formulations
  • Monitoring stability and efficacy of multi-valent vaccine formulations.-  Overcoming challenges of multi component alum formulations.-  Delivery of various TLR adjuvants using alum platform
  • History of use of emulsions for vaccine delivery
  • MF59 o/w emulsion : History and safety over the last 2 decades
  • Optimizing novel nanoemulsions for delivery of next generation antigens and adjuvants
  • Modulating vaccine responses with innate immunity : Use of PLGA nanoparticles for delivering multiple TLR agonists
  • Shape matters : Role of nanoparticle shape in induction of immune responses to a vaccine.        .

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