Targeted Therapies Mechanisms of Resistance

Targeted Therapies Mechanisms of Resistance / edited by Daniel Gioeli.

This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included.  Targeted Therapies: Mechanisms of Resistan...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Gioeli, Daniel (Editor)
Format: eBook
Language:English
Published: Totowa, NJ : Humana Press : Imprint: Humana, 2011.
Edition:1st ed. 2011.
Series:Molecular and Translational Medicine,
Springer eBook Collection.
Subjects:
Oncology  .
Molecular biology.
Cancer research.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Resistance to Targeted Therapies As a Result of Mutation(s) in the Target.- The Dynamics of the Cell Signaling Network; Implications for Targeted Therapies.- Cancer Signaling Network Analysis by Quantitative Mass Spectrometry.-  Development and Implementation of Array Technologies for Proteomics: Clinical Implications and Applications.-  Using Phosphoflow to Study Signaling Events of Sub Populations Resistant to Current Therapies
  • Mathematical and Computational Models in Cancer
  • Somatic Evolution of Acquired Drug Resistance in Cancer
  • Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer
  • MicroRNA: A Potential Therapy Able to Target Multiple Cancer Pathways
  • Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance Mathematical and Computational Models in Cancer
  • Somatic Evolution of Acquired Drug Resistance in Cancer
  • Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer
  • MicroRNA: A Potential Therapy Able to Target Multiple Cancer Pathways
  • Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance Mathematical and Computational Models in Cancer
  • Somatic Evolution of Acquired Drug Resistance in Cancer
  • Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer
  • MicroRNA: A Potential Therapy Able to Target Multiple Cancer Pathways
  • Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance.

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