Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes by Lena Josefine Daumann.

Lena Daumanns's thesis describes structural and functional studies of the enzyme Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. It also examines the properties of small mimics of this enzyme and related binuclear metallohydrolases such as the metallo-ß-lactamases to enhance our un...

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Bibliographic Details
Main Author: Daumann, Lena Josefine (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2014.
Edition:1st ed. 2014.
Series:Springer Theses, Recognizing Outstanding Ph.D. Research,
Springer eBook Collection.
Subjects:
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Introduction
  • Experimental
  • Understanding the Overall Structure of GpdQ and Metal Binding
  • Structural and Mechanistic Studies of Zn(II) Complexes as Phosphoesterase Models
  • Mechanistic Studies of Cd(II) Complexes as Phosphoesterase and Metallo-β-lactamase Models
  • Spectroscopic and Mechanistic Studies of Co(II) Phosphoesterase and Metallo-β-lactamase Biomimetics
  • Asymmetric Zn(II) Complexes as Structural and Functional Models for GpdQ
  • Immobilization of GpdQ and Related Models for Bioremedial Applications
  • Conclusion and Outlook.