Vascular Disruptive Agents for the Treatment of Cancer

Vascular Disruptive Agents for the Treatment of Cancer edited by Tim Meyer.

Tumour survival and growth is critically dependent on an independent blood supply. As such tumour vasculature presents an ideal target for cancer therapy that is widely applicable, accessible and genetically stable rendering it less prone to resistance. Two approaches have been explored for cancer t...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Meyer, Tim (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2010.
Edition:1st ed. 2010.
Series:Springer eBook Collection.
Subjects:
Cancer research.
Pharmacology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Development of Vascular Disrupting Agents
  • Development of Vascular Disrupting Agents
  • Pre-Clinical Development
  • The Discovery and Characterisation of Tumour Endothelial Markers
  • The Use of Animal Models in the Assessment of Tumour Vascular Disrupting Agents (VDAs)
  • Combination Therapy with Chemotherapy and VDAs
  • Lessons from Animal Imaging in Preclinical Models
  • Combining Antiangiogenic Drugs with Vascular Disrupting Agents Rationale and Mechanisms of Action
  • Imaging in the Development of Vascular Disruptive Agents
  • MRI to Assess Vascular Disruptive Agents
  • Contrast Ultrasound in Imaging Tumor Angiogenesis
  • Clinical Development
  • The Clinical Development of Tubulin Binding Vascular Disrupting Agents
  • ASA404 (DMXAA): New Concepts in Tumour Vascular Targeting Therapy
  • Vascular Disruptive Agents in Combination with Radiotherapy.

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