Novel Immunotherapeutic Approaches to the Treatment of Cancer Drug Development and Clinical Application / edited by Paul D. Rennert.

Cancer care is undergoing a radical transformation as novel technologies are directed toward new treatments and personalized medicine. The most dramatic advances in the treatment of cancer have come from therapeutics that augment the immune response to tumors. The immune checkpoint inhibitors are th...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Rennert, Paul D. (Editor)
Format: eBook
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edition:1st ed. 2016.
Series:Springer eBook Collection.
Subjects:
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Introduction
  • Enhancing the efficacy of checkpoint blockade through combination therapies
  • Novel Immunomodulatory Targets in the Immunoglobulin-Superfamily
  • Parallel Costimulation of Effector and Regulatory T Cells by OX40, GITR, TNFRSF25, CD27 and CD137
  • NK Cell Responses in Immunotherapy
  • Reversing T cell dysfunction for tumor immunotherapy
  • Immunomodulation within a single tumor site to induce systemic anti-tumor immunity
  • Novel Targets and Their Assessment for Cancer Treatment
  • The New Frontier of Antibody Drug Conjugates
  • Cellular Therapies
  • Targeting the Physicochemical, Cellular, and Immunosuppressive Properties of the Tumor Microenvironment by Depletion of Hyaluronan to Treat Cancer.