Serotonin and Sleep: Molecular, Functional and Clinical Aspects

Serotonin and Sleep: Molecular, Functional and Clinical Aspects edited by Jaime M. Monti, S. R. Pandi-Perumal, Barry L. Jacobs, David J. Nutt.

Serotonin and Sleep: Molecular, Functional, and Clinical Aspects covers the complete spectrum of the field and explores the link between the latest basic molecular, functional, and clinical aspects of serotonin and the practice of sleep medicine. The volume focuses on 24 different areas of research,...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Monti, Jaime M. (Editor), Pandi-Perumal, S. R. (Editor), Jacobs, Barry L. (Editor), Nutt, David J. (Editor)
Format: eBook
Language:English
Published: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2008.
Edition:1st ed. 2008.
Series:Springer eBook Collection.
Subjects:
Pharmacology.
Molecular biology.
Human physiology.
Neurosciences.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Evolution of concepts
  • Changing concepts on the role of serotonin in the regulation of sleep and waking
  • The dorsal raphe nucleus and median raphe nucleus: organization and projections
  • Topographic organization and chemoarchitecture of the dorsal raphe nucleus and the median raphe nucleus
  • Efferent and afferent connections of the dorsal and median raphe nuclei in the rat
  • Reciprocal connections between the suprachiasmatic nucleus and the midbrain raphe nuclei: A putative role in the circadian control of behavioral states
  • Serotonin receptors
  • Localization of 5-HT receptors in the mammalian cortex
  • Molecular biology of 5-HT receptors
  • Electrophysiology of serotonergic neurons and the regulation of serotonin release
  • Brain serotonergic neuronal activity in behaving cats
  • Electrophysiological studies on serotonergic neurons and sleep
  • Role and origin of the GABAergic innervation of dorsal raphe serotonergic neurons
  • Regulation of serotonin release by inhibitory and excitatory amino acids
  • Neurophysiological aspects of the regulation of serotonin neurons by the orexinergic system
  • Serotonin receptors and the regulation of behavioural state
  • Serotonin and dreaming
  • Involvement of the 5-HT1A and the 5-HT1B receptor in the regulation of sleep and waking
  • Mechanisms involved in the inhibition of REM sleep by serotonin
  • Effect of 5-HT2A/2B/2C receptor agonists and antagonists on sleep and waking in laboratory animals and humans
  • Effect of the selective activation of serotonin 5-HT3 receptors on sleep and waking
  • 5-HT7 receptor modulation of sleep patterns
  • Sleep and waking in mutant mice that do not express various proteins involved in serotonergic neurotransmission such as the serotonergic transporter, monoamine oxidase A, and 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT7 receptors
  • Circadian control by serotonin and melatonin receptors: Clinical relevance
  • Serotonergic mechanisms contributing to arousal and alerting
  • Relevance of serotonin to clinical disorders and drug actions
  • Contribution of chemosensitive serotonergic neurons to interactions between the sleep-wake cycle and respiratory control
  • Obstructive sleep apnea: The potential for serotonergic pharmacotherapies
  • The effects of antidepressant drugs and 5-HT1A agonists on human sleep
  • The effect of typical and atypical antipsychotic drugs on sleep of schizophrenic patients.

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