Adverse Drug Reactions

Adverse Drug Reactions edited by Jack Uetrecht.

This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs followed by a description of...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Uetrecht, Jack (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2010.
Edition:1st ed. 2010.
Series:Handbook of Experimental Pharmacology, 196
Springer eBook Collection.
Subjects:
Pharmacology.
Immunology.
Public health.
Hepatology.
Dermatology.
Allergy.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Description
Summary:This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs followed by a description of what are presently believed to be mediators and biochemical pathways involved in idiosyncratic drug reactions. There is also a description of several examples of ADRs that serve to illustrate specific aspects of ADR mechanisms. Eventually the book shows that ultimately better methods are needed to predict which drug candidates are likely to cause ADRs and which patients are at increased risk. But at present research seems to be far from this goal.
Physical Description:X, 556 p. 4 illus. in color. online resource.
ISBN:9783642006630
ISSN:0171-2004 ;
DOI:10.1007/978-3-642-00663-0

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