Proteases in Health and Disease

Proteases in Health and Disease edited by Sajal Chakraborti, Naranjan S. Dhalla.

Proteases form one of the largest and most diverse families of enzymes known. Once considered primarily as “enzymes of digestion,” it is now clear that proteases are involved in every aspect of cellular function. Members of the diverse families of proteases act to promote cellular proteolysis found...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Chakraborti, Sajal (Editor), Dhalla, Naranjan S. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2013.
Edition:1st ed. 2013.
Series:Advances in Biochemistry in Health and Disease ; 7
Springer eBook Collection.
Subjects:
Biochemistry.
Cell biology.
Cell physiology.
Proteomics.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Part A: Molecular and Biochemical Aspects of Proteases
  • 1. An Overview of Endoplasmic Reticulum Calpain System
  • 2. Mitochondrial Calpains: Who, What, Where, When and Why?
  • 3. Role of Calpains in Calmodulin Regulated Systems
  • 4. Exercise and Matrix Metalloproteases: A Brief Overview
  • 5. Regulation of Chondrocyte Matrix Metalloproteinase Gene Expression
  • 6. Microbial Source of Fibrinolytic Protease and Its Biotechnological Potential
  • 7. Aspartic Proteolytic Inhibitors Induce Cellular and Biochemical Alterations in Fungal Cells
  • 8. Cysteine Proteases of Human Malaria Parasites
  • 9. Proteases as Virulence Factors in Leishmania: Focus on Serine Proteases as Possible Therapeutic Targets
  • 10. An Updated Inventory on Properties, Pathophysiology and Therapeutic Potential of Snake Venom Thrombin-like Proteases
  • 11. Macrocyclic Protease Inhibitors Constrained into a β-Strand Geometry
  • Part B: Involvement of Proteases in Disease Processes
  • 12. Regulation of MT1-MMP Activation and Its Relevance to Disease Processes
  • 13. Role of Proteases During Intra-erythrocytic Developmental Cycle of Human Malaria Parasite Plasmodium falciparum
  • 14. Proteases in Vibrio cholerae and Their Role in Pathogenesis
  • 15. ADAMTS13: The von Willebrand Factor Cleaving Protease and Its Role in Thrombotic Thrombocytopenic Purpura
  • 16. Role of Proteases and Their Tissue Inhibitors in Pregnancy Outcome
  • 17. Matrix Metalloproteinases in Bone Health and Disease
  • 18. Escalated Expression of Matrix Metalloproteinases in Osteoarthritis
  • 19. Role of Proteases in Autism Spectrum Disorder
  • 20. Role of Proteases in the Management of Hepatitis C Virus
  • 21. Role of Protease in Inflammatory Lung Diseases
  • 22. Involvement of Some Proteolytic Enzymes in Cardiac Dysfunction Due to Ischemia-Reperfusion Injury.

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