Key Clinical Trials in Erectile Dysfunction by Culley C. Carson.

This book represents a critical appraisal of the major clinical trials that have had a significant impact on clinical research and practice during the last decade. Each trial follows a strict format, starting with reference to the original source of publication, details on the key investigators and...

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Bibliographic Details
Main Author: Carson, Culley C. (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: London : Springer London : Imprint: Springer, 2007.
Edition:1st ed. 2007.
Series:Springer eBook Collection.
Subjects:
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • The Earliest Carefully Controlled Clinical Trial Evaluating Oral Pharmacotherapy (Yohimbine) in ED
  • A Description of the Pioneering Work That Led to the First Approved Agents for ED: Giles Brindley, the Needle, and the Penis (Phenoxybenzamine)
  • The Pivotal Study Showing That Intracorporal Injection of Vasoactive Agents (Papaverine or Phenoxybenzamine) Was Effective Pharmacotherapy
  • The First Placebo-Controlled Study on the Benefits of Intracorporal Administration of Vasorelaxant Agents to ED Patients (Papaverine/Phentolamine Combination)
  • Representative Study on the Use of Yohimbine in the Treatment of Organic ED
  • Defining the Therapeutic Ratio for Intracavernosal Administration of Prostaglandin E1 (Alprostadil)
  • An Elegant Long-Term Trial Assessing the Clinical Profile of Intracavernosal Prostaglandin E1 (Alprostadil)
  • Evaluation of Novel Combination (Vasoactive Intestinal Polypeptide and Phentolamine) as Intracavernosal Therapy
  • Now-Classic Study on the Use of Intraurethral Prostaglandin E1 (Alprostadil)
  • Route of Administration Has a Considerable Impact on Clinical Profile: A Comparison of Intraurethral and Intracavernosal Alprostadil
  • First Clinical Data on Sildenafil: The Arrival of Oral Pharmacotherapy
  • Original “Gold Standard” Clinical Trial of Sildenafil in ED
  • Pilot Study Showing Benefit of Clinical Response to Apomorphine Sublingual (SL)
  • A Viable Alternative to PDE Inhibitors: Definition of Therapeutic Ratio of Apomorphine Sublingual (SL) in Patients with ED
  • Summary of Clinical Trials of Phentolamine
  • Impact of Testosterone Replacement in Androgen-Deficient Males
  • Evaluation of Psychotherapy for Patients and Partners
  • Quantification of Benefit of a Vacuum Device on Erectile Function
  • Pioneering Clinical Trial of Surgical Procedures.