|
|
|
|
LEADER |
00000nam a22000005i 4500 |
001 |
b3313001 |
003 |
MWH |
005 |
20191026193026.0 |
007 |
cr nn 008mamaa |
008 |
100301s2008 xxu| s |||| 0|eng d |
020 |
|
|
|a 9781597452922
|
024 |
7 |
|
|a 10.1007/978-1-59745-292-2
|2 doi
|
035 |
|
|
|a (DE-He213)978-1-59745-292-2
|
050 |
|
4 |
|a E-Book
|
072 |
|
7 |
|a MJCL
|2 bicssc
|
072 |
|
7 |
|a MED062000
|2 bisacsh
|
072 |
|
7 |
|a MJCL
|2 thema
|
245 |
1 |
0 |
|a Transforming Growth Factor-Beta in Cancer Therapy, Volume I
|h [electronic resource] :
|b Basic and Clinical Biology /
|c edited by Sonia B. Jakowlew.
|
250 |
|
|
|a 1st ed. 2008.
|
264 |
|
1 |
|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2008.
|
300 |
|
|
|a XXIV, 735 p.
|b online resource.
|
336 |
|
|
|a text
|b txt
|2 rdacontent
|
337 |
|
|
|a computer
|b c
|2 rdamedia
|
338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
347 |
|
|
|a text file
|b PDF
|2 rda
|
490 |
1 |
|
|a Cancer Drug Discovery and Development,
|x 2196-9906
|
490 |
1 |
|
|a Springer eBook Collection
|
505 |
0 |
|
|a Basic Concepts of TGF-? Signaling in Normal Physiology and Cancer Pathobiology -- Component Hardware for Transforming Growth Factor-? Signal Transduction: TGF-? Ligands, TGF-? Receptors, and Smads -- TGF-? Signaling in Homeostasis and Cancer -- TGF-? Availability: Latent TGF-? and Latent TGF-? Binding Proteins -- Biological Functions of Latent TGF-?-Binding Proteins and Activation of TGF-? -- Regulators of Smad2/3 Transcription and Phosphorylation -- Interaction of Smad4 and Embryonic Liver Fodrin-?-spectrin in Hyperplasia, Neoplasia, and Tumor Suppression -- Regulation of Smad Activity by Phosphorylation -- Nuclear Targeting of TGF-?-Activated Smads in Normal and Tumor Biology -- Ski, SnoN, and Akt as Negative Regulators of Smad Activity: Balancing Cell Death and Cell Survival -- Transforming Growth Factor-? in Cancer Therapy: Smurfs in TGF-? Signaling and Regulation of Bone Homeostasis and Cancer -- Involvement of km23 Dynein Light Chains in TGF ? Signaling -- TGF-? Signaling in Fibroblastic Cells and Oncogenesis -- Mechanisms of TGF-?-Induced Apoptosis in Cancer Cells -- Mechanisms of Cell Cycle Regulation by TGF-? Disabled in Cancer -- Transforming Growth Factor-? in Cancer Therapy -- TGF-? and Smad Signaling in Transcriptome Reprogramming During EMT -- Functional Interactions Between MMPs and TGF-? in Normal and Tumor Tissue -- Cooperation Between TGF-? and Wnt Pathway Components in Regulating Mesenchymal Stem Cell Function -- Interaction of Oncogenic Ras and TGF?1 Signaling in Cancer: Lessons From the Multistage Skin Carcinogenesis Model -- TGF-? Superfamily Members in Normal and Tumor Biology -- Proteomics Analysis of TGF? Superfamily Members -- Mullerian Inhibiting Substance: A Potential Nontoxic, Naturally Occurring Therapeutic Agent for Certain Human Cancers -- Activins, Inhibins, and Bone Morphogenetic Proteins as Modulators and Biomarkers of Prostate Cancer Progression -- Bone Morphogenic Proteins and Angiogenesis in Developing Tumors -- Histone Methyltransferase and Smad Interactions in BMP Signaling -- Endoglin (CD105): A Strong Candidate for Immunologic Targeting of Tumor Neovasculature in Human Malignancies -- Activins and Inhibins in Cancer Progression -- Bone Morphogenetic Proteins/Growth Differentiation Factors and Smad Activation in Ovarian Granulosa Cells and Carcinoma -- Regulation of the Transforming Growth Factor-? Superfamily by Betaglycan -- Uterine Sensitization Associated Gene-1: A Bone Morphogenetic Protein Antagonist with a Role in Kidney -- Role of Betaig-h3 Gene in Carcinogenesis -- Activins and the Liver -- Myostatin Signaling in Normal and Tumor Cells -- TGF-? in Inflammation and Fibrosis -- Triterpenoids, Vitamin D, and TGF-?/Smad Signaling in Inflammation and Cancer -- Thrombospondin-Dependent Activation of Latent TGF-? in Fibrosis and Disease -- TGF-? in Pulmonary Fibrosis -- The Role of TGF-? in Bleomycin Induced Pulmonary Fibrosis -- Smads in the Fibrotic Response: Findings in the Smad3 Knockout Mouse -- TGF-? Signaling in Renal Fibrosis and Inflammation: Gene Therapy Using Ultrasound-Microbubble-Mediated Inducible Smad7 -- Transforming Growth Factor-? Peptide Signaling in Pulmonary Development, Bronchopulmonary Dysplasia, Fibrosis, and Emphysema -- The Role of TGF-? in Radiation and Chemotherapy Induced Pulmonary Fibrosis: Inhibition of TGF-? as a Novel Therapeutic Strategy -- Negative Regulation of the TGF-? Family Signal Pathway by Inhibitory Smads and Their Involvement in Cancer and Fibrosis -- TGF-?-Related Antifibrotic Strategies in the Eye -- Transforming Growth Factor-? in Cutaneous Tissue Repair -- Topical Application of TGF-?1 Peptide Inhibitors for the Therapy of Skin Fibrosis -- Overexpressed Truncated TGF-? Type II Receptor Inhibits Fibrotic Behavior of Keloid Fibroblasts In Vitro and Experimental Scar Formation In Vivo.
|
520 |
|
|
|a Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide a compendium of findings about the role of transforming growth factor-ß (TGF-ß) in cancer treatment and therapy. The first volume, Basic and Clinical Biology, is divided into three parts. Part I presents basic concepts of transforming growth factor-ß signaling in normal physiology and cancer pathobiology. Part II investigates transforming growth factor-ß superfamily members in normal and tumor biology. Part III details transforming growth factor-ß in inflammation and fibrosis. This volume’s companion, Cancer Treatment and Therapy, examines transforming growth factor-ß in several developing and advanced cancers and discusses methods of treatment and therapy. Together, Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide researchers and clinicians with a comprehensive and cutting-edge reference for the findings about the role of transforming growth factor-ß in biology and cancer treatment.
|
590 |
|
|
|a Loaded electronically.
|
590 |
|
|
|a Electronic access restricted to members of the Holy Cross Community.
|
650 |
|
0 |
|a Oncology .
|
650 |
|
0 |
|a Cell biology.
|
650 |
|
0 |
|a Cancer research.
|
650 |
|
0 |
|a Pharmacology.
|
690 |
|
|
|a Electronic resources (E-books)
|
700 |
1 |
|
|a Jakowlew, Sonia B.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
|
710 |
2 |
|
|a SpringerLink (Online service)
|
773 |
0 |
|
|t Springer eBooks
|
830 |
|
0 |
|a Cancer Drug Discovery and Development,
|x 2196-9906
|
830 |
|
0 |
|a Springer eBook Collection.
|
856 |
4 |
0 |
|u https://holycross.idm.oclc.org/login?auth=cas&url=https://doi.org/10.1007/978-1-59745-292-2
|3 Click to view e-book
|
907 |
|
|
|a .b33130012
|b 04-18-22
|c 02-26-20
|
998 |
|
|
|a he
|b 02-26-20
|c m
|d @
|e -
|f eng
|g xxu
|h 0
|i 1
|
912 |
|
|
|a ZDB-2-SME
|
950 |
|
|
|a Medicine (Springer-11650)
|
902 |
|
|
|a springer purchased ebooks
|
903 |
|
|
|a SEB-COLL
|
945 |
|
|
|f - -
|g 1
|h 0
|j - -
|k - -
|l he
|o -
|p $0.00
|q -
|r -
|s b
|t 38
|u 0
|v 0
|w 0
|x 0
|y .i22261631
|z 02-26-20
|
999 |
f |
f |
|i 06a2fd34-0185-5f2d-9a34-e2ab33a842e8
|s f9d5c9a8-a351-5191-b7dc-a7bd5d7ad980
|
952 |
f |
f |
|p Online
|a College of the Holy Cross
|b Main Campus
|c E-Resources
|d Online
|e E-Book
|h Library of Congress classification
|i Elec File
|n 1
|