Sigma Receptors Chemistry, Cell Biology and Clinical Implications

Sigma Receptors Chemistry, Cell Biology and Clinical Implications / edited by Rae R. Matsumoto, Wayne D. Bowen, Tsung Ping Su.

Sigma receptors are promising drug development targets for a host of neurological, psychiatric, oncological, immunological, cardiovascular, ophthalmological, and gastrointestinal disorders. They are structurally unique proteins that are distinct from classical G protein-coupled receptors, ionotropic...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Matsumoto, Rae R. (Editor), Bowen, Wayne D. (Editor), Su, Tsung Ping (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 2007.
Edition:1st ed. 2007.
Series:Springer eBook Collection.
Subjects:
Neurosciences.
Chemistry.
Pharmacology.
Biochemistry.
Cell biology.
Psychiatry.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • ? Receptors: Historical Perspective and Background
  • Medicinal Chemistry: New Chemical Classes and Subtype-Selective Ligands
  • Irreversible ? Compounds
  • Pharmacophore Models for ?1 Receptor Binding
  • Cloning of ?1 Receptor and Structural Analysis of Its Gene and Promoter Region
  • Site-Directed Mutagenesis
  • ? Receptor Modulation of Ion Channels
  • Subcellular Localization and Interacellular Dynamics of ?1 Receptors
  • Intracellular Signaling and Synaptic Plasticity
  • Modulation of Classical Neurotransmitter Systems by ? Receptors
  • ?2 Receptors: Regulation of Cell Growth and Implications for Cancer Diagnosis and Therapeutics
  • Cognitive Effects of ? Receptor Ligands
  • ? Receptors and Scizophrenia
  • Potential Role of ? Ligands and Neurosteroids in Major Depression
  • ? Receptors and Drug Abuse
  • ?1 Receptors and the Modulation of Opiate Analgesics
  • ? Receptors in the Immune System: Implications for Potential Therapeutic Intervention - An Overview
  • ? Receptors and Gastrointestinal Function.

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