Systems Biology of RNA Binding Proteins

Systems Biology of RNA Binding Proteins edited by Gene W. Yeo.

After transcription in the nucleus, RNA binding proteins (RBPs) recognize cis-regulatory RNA elements within pre-mRNA sequence to form mRNA-protein (mRNP) complexes. Similarly to DNA binding proteins such as transcription factors that regulate gene expression by binding to DNA elements in the promot...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Yeo, Gene W. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2014.
Edition:1st ed. 2014.
Series:Advances in Experimental Medicine and Biology, 825
Springer eBook Collection.
Subjects:
Systems biology.
Proteins .
Gene expression.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Encyclopedia of RNA binding protein expression and domain annotations
  • RNA localization and RNA binding proteins that control localization
  • Genome-wide approaches to studying alternative polyadenylation events and the RBPs that control them
  • RNA binding proteins, PRC complex and long ncRNAs
  • Gene and genome regulation by piwi proteins
  • Engineering Artificial RBP interactions
  • Querying functional polymorphisms by high throughput binding and functional assays
  • RNA binding protein networks in EMT/MET
  • Therapies against diseases associated with RNA processing defects and RNA binding proteins
  • Repeat-disorders and the RNA binding proteins implicated in them
  • RNA binding proteins in heart development
  • Identification of miRNAs and their targets in C elegans
  • Splicing code
  • Index.

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