Th 17 Cells: Role in Inflammation and Autoimmune Disease

Th 17 Cells: Role in Inflammation and Autoimmune Disease edited by Valérie Quesniaux, Bernhard Ryffel, Franco Di Padova.

With the recent definition of the Th17 cell subset, a new paradigm in innate and adaptive immunity has been established. This book describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. The mechanism by which this T cell subset is generate...

Full description

Saved in:
Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Quesniaux, Valérie (Editor), Ryffel, Bernhard (Editor), Di Padova, Franco (Editor)
Format: eBook
Language:English
Published: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2009.
Edition:1st ed. 2009.
Series:Progress in Inflammation Research,
Springer eBook Collection.
Subjects:
Immunology.
Cell biology.
Rheumatology.
Allergy.
Infectious diseases.
Pharmacology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Description
Summary:With the recent definition of the Th17 cell subset, a new paradigm in innate and adaptive immunity has been established. This book describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. The mechanism by which this T cell subset is generated and maintained shows specific differences between mice and man which are reviewed. One characteristic of Th17 cells is to secrete specific and unique cytokines such as IL-17A, IL-17F and IL-22; their functions are described in detail. These cytokines have acquired a prevalent role in many pathological conditions in animal models and in humans. Targeting these cytokines as well as the generation of Th17 cells may open new ways to treat many autoimmune diseases. The role of Th17 in infectious conditions is also addressed.
Physical Description:XII, 244 p. 20 illus. online resource.
ISBN:9783764386818
ISSN:0379-0363
DOI:10.1007/978-3-7643-8681-8

Similar Items