Chemokine Biology - Basic Research and Clinical Application Vol. 2: Pathophysiology of Chemokines

Chemokine Biology - Basic Research and Clinical Application Vol. 2: Pathophysiology of Chemokines / edited by Kuldeep Neote, L. Gordon Letts, Bernhard Moser.

Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, a...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Neote, Kuldeep (Editor), Letts, L. Gordon (Editor), Moser, Bernhard (Editor)
Format: eBook
Language:English
Published: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2007.
Edition:1st ed. 2007.
Series:Progress in Inflammation Research,
Springer eBook Collection.
Subjects:
Immunology.
Pharmacology.
Cell biology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Chemokines in animal disease models
  • Chemokines in animal models of inflammation
  • Autoimmune diseases
  • Chemokines in allergic responses: eosinophils, basophils, mast cells
  • Chemokines as drug targets
  • Chemokines as drug targets
  • Screening and characterization of cyclic pentapeptide CXCR4 antagonists/inverse agonists using a pheromone responsive reporter gene in Saccharomyces cerevisiae: Utility of G protein coupled receptor constitutively active mutants
  • Antagonists of CXCR3: a review of current progress
  • IL-8 receptor antagonist: basic research and clinical utility
  • Current status of CCR1 antagonists in clinical trials
  • Small molecule CCR2 antagonists
  • Chemokine axes in hematopoietic stem cell mobilization
  • CCR5 antagonists: from discovery to clinical efficacy.

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