Structure, function, and modulation of neuronal voltage-gated ion channels / Valentin K. Gribkoff, Leonard K. Kaczmarek.

This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly...

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Bibliographic Details
Main Author: Gribkoff, Valentin K.
Other Authors: Kaczmarek, Leonard K.
Format: eBook
Language:English
Published: Hoboken, N.J. : Wiley, ©2009.
Subjects:
Online Access:Click for online access

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100 1 |a Gribkoff, Valentin K. 
245 1 0 |a Structure, function, and modulation of neuronal voltage-gated ion channels /  |c Valentin K. Gribkoff, Leonard K. Kaczmarek. 
260 |a Hoboken, N.J. :  |b Wiley,  |c ©2009. 
300 |a 1 online resource (xiv, 475 pages, 12 unnumbered pages of plates) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
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504 |a Includes bibliographical references and index. 
505 0 |a STRUCTURE, FUNCTION, AND MODULATION OF NEURONAL VOLTAGE-GATED ION CHANNELS; CONTENTS; Preface; Contributors; PART I NEURONAL VOLTAGE-GATED ION CHANNEL FUNCTIONS; 1 Neuronal L-Type Voltage-Gated Calcium Channels; 2 Voltage-Gated N-Type and T-Type Calcium Channels and Excitability Disorders; 3 Voltage-Gated Sodium Channels: Multiple Roles in the Pathophysiology of Pain; 4 The Role of Ion Channels in the Etiology and Development of Gliomas; 5 Shaker Family K(v)1 Voltage-Gated Potassium Channels in Mammalian Brain Neurons. 
520 |a This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly important role of ion channel screening in cardiac risk assessment. It provides an important reference for research scientists and drug discovery companies. 
588 0 |a Print version record. 
650 0 |a Ion channels. 
650 0 |a Ion channels  |x Effect of drugs on. 
650 0 |a Drug development. 
650 0 |a Molecular pharmacology. 
650 7 |a MEDICAL  |x Drug Guides.  |2 bisacsh 
650 7 |a MEDICAL  |x Pharmacology.  |2 bisacsh 
650 7 |a MEDICAL  |x Pharmacy.  |2 bisacsh 
650 7 |a MEDICAL  |x Nursing  |x Pharmacology.  |2 bisacsh 
650 7 |a Drug development  |2 fast 
650 7 |a Ion channels  |2 fast 
650 7 |a Ion channels  |x Effect of drugs on  |2 fast 
650 7 |a Molecular pharmacology  |2 fast 
700 1 |a Kaczmarek, Leonard K. 
758 |i has work:  |a Structure, function, and modulation of neuronal voltage-gated ion channels (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGKmQQ87H76Rw64WmcKMmq  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |a Gribkoff, Valentin K.  |t Structure, function, and modulation of neuronal voltage-gated ion channels.  |d Hoboken, N.J. : Wiley, ©2009  |z 9780470429891  |z 0470429895  |w (DLC) 2008046707  |w (OCoLC)268957347 
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