Structure, function, and modulation of neuronal voltage-gated ion channels

Structure, function, and modulation of neuronal voltage-gated ion channels / Valentin K. Gribkoff, Leonard K. Kaczmarek.

This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly...

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Bibliographic Details
Main Author: Gribkoff, Valentin K.
Other Authors: Kaczmarek, Leonard K.
Format: eBook
Language:English
Published: Hoboken, N.J. : Wiley, ©2009.
Subjects:
Ion channels.
Ion channels > Effect of drugs on.
Drug development.
Molecular pharmacology.
MEDICAL > Drug Guides.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
MEDICAL > Nursing > Pharmacology.
Drug development
Ion channels
Ion channels > Effect of drugs on
Molecular pharmacology
Online Access:Click for online access
Table of Contents:
  • STRUCTURE, FUNCTION, AND MODULATION OF NEURONAL VOLTAGE-GATED ION CHANNELS; CONTENTS; Preface; Contributors; PART I NEURONAL VOLTAGE-GATED ION CHANNEL FUNCTIONS; 1 Neuronal L-Type Voltage-Gated Calcium Channels; 2 Voltage-Gated N-Type and T-Type Calcium Channels and Excitability Disorders; 3 Voltage-Gated Sodium Channels: Multiple Roles in the Pathophysiology of Pain; 4 The Role of Ion Channels in the Etiology and Development of Gliomas; 5 Shaker Family K(v)1 Voltage-Gated Potassium Channels in Mammalian Brain Neurons.

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