Gene action : a historical account / Werner Maas.

As a college student, Werner Maas took a course in genetics in 1941 and wondered why so little was said about the biochemical action of genes in controlling the specific function of an organism. Just at that time, biochemists and geneticists began to investigate jointly the basis of gene action, esp...

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Bibliographic Details
Main Author: Maas, Werner Karl, 1921-
Format: eBook
Language:English
Published: Oxford ; New York : Oxford University Press, 2001.
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Online Access:Click for online access

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245 1 0 |a Gene action :  |b a historical account /  |c Werner Maas. 
260 |a Oxford ;  |a New York :  |b Oxford University Press,  |c 2001. 
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504 |a "Appendix": pages 145-156. 
504 |a Includes bibliographical references and index. 
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520 |a As a college student, Werner Maas took a course in genetics in 1941 and wondered why so little was said about the biochemical action of genes in controlling the specific function of an organism. Just at that time, biochemists and geneticists began to investigate jointly the basis of gene action, especially in microorganisms. Thus, Maas was able to witness firsthand the spectacular developments that led in the next twenty-five years to a clear picture of the action of genes. The history of these remarkable discoveries is the core of this book. After 1965, building on insights gained from the work with microorganisms, studies of gene action turned to animals and plants and concentrated on processes not present in microorganisms, such as embryonic development, the role of genes in diseases, and the function of the nervous system. Because of the rapidity of technical advances made in handling genes, it has been possible to learn much about these complex processes. The last part of the book deals with these developments, which are ongoing parts of the history of gene action. 
505 0 |a Contents -- I: The Classical Period, 1860â€?1940 -- 1 Overture: The Garden of Mendel -- 2 Building a Scaffold: Genes Within Chromosomes -- II: One Geneâ€?One Enzyme, 1900â€?1953 -- 3 The Dawn of the One Geneâ€?One Enzyme Hypothesis During the Classical Period -- 4 The Neurospora Era -- 5 Escherichia coli Enters the Field -- 6 Biochemical Genetics in Escherichia coli -- 7 The Chemical Nature of Genes -- III: How Genes Determine Protein Structure, 1953â€?1965 -- 8 Building a Theoretical Framework for Gene Action -- 9 Biochemical Identification of Adaptors 
505 8 |a 10 The Elusive Messenger11 Deciphering the Code -- IV: Regulation or Gene Action -- 12 Feedback Control of Biosynthetic Pathways -- 13 Adaptive Enzymes -- 14 The Operon Model -- V: In the Aftermath of the Operon Model, 1965â€?2000 -- 15 The Floodgates Open -- Appendix: Further Readings and Comments -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- R -- S -- T -- U -- V -- W -- X -- Y -- Z 
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