Human genome epidemiology : building the evidence for using genetic information to improve health and prevent disease / edited by Muin J. Khoury [and others].

This text describes the role that epidemiologic methods play in the continuum from gene discovery to the development and application of genetic tests. It provides a foundation that should help researchers, policy makers and practitioners integrate genomics into medical and public health practice.

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Bibliographic Details
Other Authors: Khoury, Muin J.
Format: eBook
Language:English
Published: New York ; Oxford : Oxford University Press, 2010.
Edition:2nd ed.
Subjects:
Online Access:Click for online access

MARC

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245 0 0 |a Human genome epidemiology :  |b building the evidence for using genetic information to improve health and prevent disease /  |c edited by Muin J. Khoury [and others]. 
250 |a 2nd ed. 
260 |a New York ;  |a Oxford :  |b Oxford University Press,  |c 2010. 
300 |a 1 online resource (xxiii, 676 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
520 8 |a This text describes the role that epidemiologic methods play in the continuum from gene discovery to the development and application of genetic tests. It provides a foundation that should help researchers, policy makers and practitioners integrate genomics into medical and public health practice. 
505 0 |a Human genome epidemiology: the road map revisited -- Principles of analysis of germline genetics -- The public health genomics enterprise -- Navigating the evolving knowledge of human genetic variation in health and disease -- The global emergence of epidemiological biobanks: opportunities and challenges -- Case-control and cohort studies in the age of genome-wide associations -- The emergence of networks in human genome epidemiology: challenges and opportunities -- Design and analysis issues in genome-wide association studies -- The challenge of assessing complex gene-environment and gene-gene interactions -- STrengthening the REporting of genetic association studies (STREGA)-an extension of the STROBE statement -- Integration of the evidence on gene-disease associations: methods of HuGE reviews -- Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases -- Colorectal cancer -- Childhood leukemias -- Bladder cancer -- Type 2 diabetes -- Osteoporosis -- Preterm birth -- Coronary heart disease -- Schizophrenia -- Mendelian randomization: the contribution of genetic epidemiology to elucidating environmentally modifiable causes of disease -- Evaluation of predictive genetic tests for common diseases: bridging epidemiological, clinical, and public health measures -- The evaluation of genomic applications in practice and prevention (EGAPP) initiative: methods of the EGAPP working group -- Rapid, evidence-based reviews of genetic tests -- Role of social and behavioral research in assessing the utility of genetic information -- Assessing the evidence for clinical utility in newborn screening -- The role of epidemiology in assessing the potential clinical impact of pharmacogenomics -- The human epigenome and cancer -- The use of family history in public health practice: the epidemiologic view -- Cytochrome P450 testing in the treatment of depression -- A rapid-ACCE review of CYP2CP and VKORC1 allele testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding -- Hereditary hemochromatosis: population screening for gene mutations. 
588 0 |a Print version record. 
546 |a English. 
650 0 |a Genetic disorders  |x Epidemiology. 
650 0 |a Medical genetics  |x Methodology. 
650 0 |a Genomics. 
650 0 |a Genetic screening. 
650 0 |a Human genome. 
650 7 |a Human genome  |2 fast 
650 7 |a Genetic screening  |2 fast 
650 7 |a Genomics  |2 fast 
700 1 |a Khoury, Muin J. 
776 0 8 |i Print version  |z 9780195398441 
856 4 0 |u https://holycross.idm.oclc.org/login?auth=cas&url=https://academic.oup.com/book/34832  |y Click for online access 
903 |a OUP-SOEBA 
994 |a 92  |b HCD