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|c edited by Alex Dmitrienko, Ajit C. Tamhane, Frank Bretz.
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|b Chapman & Hall/CRC,
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|a Includes bibliographical references and index.
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|a 1. Multiplicity problems in clinical trials : a regulatory perspective / Mohammad Huque and Joachim Rèohmel -- 2. Multiple testing methodology / Alex Dmitrienko [and others] -- 3. Multiple testing in dose-response problems / Frank Bretz, Ajit C. Tamhane, and Josâe Pinheiro -- 4. Analysis of multiple endpoints in clinical trials / Ajit C. Tamhane and Alex Dmitrienko -- 5. Gatekeeping procedures in clinical trials / Alex Dmitrienko and Ajit C. Tamhane -- 6. Adaptive designs and confirmatory hypothesis testing / Willi Maurer, Michael Branson, and Martin Posch -- 7. Design and analysis of microarray experiments for pharmacogenomics / Jason C. Hsu [and others].
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|a Useful Statistical Approaches for Addressing Multiplicity Issues Includes practical examples from recent trials Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple comparison research with an emphasis on pharmaceutical applications. In each chapter, the expert contributors describe important multiplicity problems encountered in pre-clinical and clinical trial settings. The book begins with a broad introduction.
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|a Tamhane, Ajit C.
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|a Multiple Testing Problems in Pharmaceutical Statistics (Text)
|1 https://id.oclc.org/worldcat/entity/E39PD3rDbpp3dHH9qTRQQHVtDm
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|i Print version:
|t Multiple testing problems in pharmaceutical statistics.
|d Boca Raton, FL : Chapman & Hall/CRC, ©2010
|z 9781584889847
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|w (OCoLC)444337350
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|a Chapman & Hall/CRC biostatistics series ;
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